MicroRNA schizophrenia: etiology, biomarkers and therapeutic targets
HC Zhang, Y Du, L Chen, ZQ Yuan, Y Cheng - … & Biobehavioral Reviews, 2023 - Elsevier
The three sets of symptoms associated with schizophrenia—positive, negative, and
cognitive—are burdensome and have serious effects on public health, which affects up to …
cognitive—are burdensome and have serious effects on public health, which affects up to …
[HTML][HTML] Schizophrenia: a narrative review of etiopathogenetic, diagnostic and treatment aspects
L Orsolini, S Pompili, U Volpe - Journal of Clinical Medicine, 2022 - mdpi.com
Although schizophrenia is currently conceptualized as being characterized as a syndrome
that includes a collection of signs and symptoms, there is strong evidence of heterogeneous …
that includes a collection of signs and symptoms, there is strong evidence of heterogeneous …
[HTML][HTML] Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week …
MH Zhu, ZJ Liu, QY Hu, JY Yang, Y Jin, N Zhu… - Military Medical …, 2022 - Springer
Background Although clozapine is an effective option for treatment-resistant schizophrenia
(TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main …
(TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main …
[HTML][HTML] Abnormal synaptic plasticity and impaired cognition in schizophrenia
XL Wu, QJ Yan, F Zhu - World journal of psychiatry, 2022 - ncbi.nlm.nih.gov
Schizophrenia (SCZ) is a severe mental illness that affects several brain domains with
relation to cognition and behaviour. SCZ symptoms are typically classified into three …
relation to cognition and behaviour. SCZ symptoms are typically classified into three …
[HTML][HTML] Associations of genetic polymorphisms and neuroimmune markers with some parameters of frontal lobe dysfunction in schizophrenia
A Morozova, Y Zorkina, K Pavlov, O Pavlova… - Frontiers in …, 2021 - frontiersin.org
We investigated the associations of DRD3 rs6280, HTR1A rs6295, BDNF rs6265, SCL6A4
rs16965628, and 5HT2A rs7322347 with schizophrenia in a case–control study, and …
rs16965628, and 5HT2A rs7322347 with schizophrenia in a case–control study, and …
Loss of the Schizophrenia-linked Furin protein from Drosophila mushroom body neurons results in antipsychotic-reversible habituation deficits
K Foka, EM Georganta, O Semelidou… - Journal of …, 2022 - Soc Neuroscience
Habituation is a conserved adaptive process essential for incoming information assessment,
which drives the behavioral response decrement to recurrent inconsequential stimuli and …
which drives the behavioral response decrement to recurrent inconsequential stimuli and …
[HTML][HTML] Genotypic and Haplotypic Association of Catechol-O-Methyltransferase rs4680 and rs4818 Gene Polymorphisms with Particular Clinical Symptoms in …
Catechol-O-methyl transferase (COMT) gene variants are involved in different
neuropsychiatric disorders and cognitive impairments, associated with altered dopamine …
neuropsychiatric disorders and cognitive impairments, associated with altered dopamine …
[HTML][HTML] A new aspect on the correlation of ten SNPs in MIR and their target genes in dopaminergic pathways in schizophrenia
A Molaei, M Agahi, M Malekian, B Moradhasel… - Bulletin of the National …, 2022 - Springer
Background Schizophrenia (SCZ) is a severe mental disorder in which people interpret
reality abnormally. Different studies indicated a complex polygenic control over SCZ. In the …
reality abnormally. Different studies indicated a complex polygenic control over SCZ. In the …
[HTML][HTML] Childhood traumatic events and the dopaminergic theory of psychosis: A mini-review of studies investigating gene–environment interactions
There is great body of evidence showing a relationship between childhood adversity and
psychosis onset. Genetic factors moderate the association between childhood adversity and …
psychosis onset. Genetic factors moderate the association between childhood adversity and …
Association of GAD1 gene polymorphism rs3749034 with the information processing and cognitive event-related potentials in schizophrenia patients and healthy …
ZI Storozheva, AV Kirenskaya, DV Samylkin… - Clinical …, 2024 - Elsevier
Objective Glutamic acid decarboxylase, an enzyme in GABA biosynthesis, is encoded by the
GAD1 gene, the transcriptional activity of which is affected by the rs3749034 polymorphism …
GAD1 gene, the transcriptional activity of which is affected by the rs3749034 polymorphism …