The three sets of symptoms associated with schizophrenia—positive, negative, and
cognitive—are burdensome and have serious effects on public health, which affects up to …

Although schizophrenia is currently conceptualized as being characterized as a syndrome
that includes a collection of signs and symptoms, there is strong evidence of heterogeneous …

Background Although clozapine is an effective option for treatment-resistant schizophrenia
(TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main …

Schizophrenia (SCZ) is a severe mental illness that affects several brain domains with
relation to cognition and behaviour. SCZ symptoms are typically classified into three …

We investigated the associations of DRD3 rs6280, HTR1A rs6295, BDNF rs6265, SCL6A4
rs16965628, and 5HT2A rs7322347 with schizophrenia in a case–control study, and …

Habituation is a conserved adaptive process essential for incoming information assessment,
which drives the behavioral response decrement to recurrent inconsequential stimuli and …

Catechol-O-methyl transferase (COMT) gene variants are involved in different
neuropsychiatric disorders and cognitive impairments, associated with altered dopamine …

Background Schizophrenia (SCZ) is a severe mental disorder in which people interpret
reality abnormally. Different studies indicated a complex polygenic control over SCZ. In the …

There is great body of evidence showing a relationship between childhood adversity and
psychosis onset. Genetic factors moderate the association between childhood adversity and …

Objective Glutamic acid decarboxylase, an enzyme in GABA biosynthesis, is encoded by the
GAD1 gene, the transcriptional activity of which is affected by the rs3749034 polymorphism …