Cerebral cavernous malformation: from mechanism to therapy

DA Snellings, CC Hong, AA Ren… - Circulation …, 2021 - Am Heart Assoc
Cerebral cavernous malformations are acquired vascular anomalies that constitute a
common cause of central nervous system hemorrhage and stroke. The past 2 decades have …

[HTML][HTML] Mining microbes for mental health: determining the role of microbial metabolic pathways in human brain health and disease

S Spichak, TFS Bastiaanssen, K Berding… - Neuroscience & …, 2021 - Elsevier
There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

Childhood stroke

PB Sporns, HJ Fullerton, S Lee, H Kim, WD Lo… - Nature Reviews …, 2022 - nature.com
Stroke is an important cause of neurological morbidity in children; most survivors have
permanent neurological deficits that affect the remainder of their life. Stroke in childhood, the …

Gut microbes in cerebrovascular diseases: gut flora imbalance, potential impact mechanisms and promising treatment strategies

X Zou, L Wang, L Xiao, S Wang, L Zhang - Frontiers in immunology, 2022 - frontiersin.org
The high morbidity, mortality, and disability rates associated with cerebrovascular disease
(CeVD) pose a severe danger to human health. Gut bacteria significantly affect the onset …

Neuroinflammation plays a critical role in cerebral cavernous malformation disease

CC Lai, B Nelsen, E Frias-Anaya… - Circulation …, 2022 - Am Heart Assoc
Background: Cerebral cavernous malformations (CCMs) are neurovascular lesions caused
by loss of function mutations in 1 of 3 genes, including KRIT1 (CCM1), CCM2, and PDCD10 …

The role of the gut microbiome and its metabolites in cerebrovascular diseases

H Xu, Z Xu, S Long, Z Li, J Jiang, Q Zhou… - Frontiers in …, 2023 - frontiersin.org
The gut microbiome is critically involved in maintaining normal physiological function in the
host. Recent studies have revealed that alterations in the gut microbiome contribute to the …

Gut microbiota: A new insight into neurological diseases

L Liu, H Wang, X Chen, P Xie - Chinese Medical Journal, 2023 - journals.lww.com
In the last decade, it has become increasingly recognized that a balanced gut microbiota
plays an important role in maintaining the health of the host. Numerous clinical and …

Cerebral cavernous malformations: Typical and atypical imaging characteristics

D Kuroedov, B Cunha, J Pamplona… - Journal of …, 2023 - Wiley Online Library
Cavernous malformations (CMs) are benign vascular malformations that maybe seen
anywhere in the central nervous system. They are dynamic lesions, growing or shrinking …

Gut dysbiosis is associated with the severity of cryptogenic stroke and enhanced systemic inflammatory response

Q Zheng, Y Chen, Y Zhai, L Meng, H Liu… - Frontiers in …, 2022 - frontiersin.org
Studies implicate that gut dysbiosis is related with many neurological diseases. However,
the potential role of gut dysbiosis in cryptogenic stroke (CS) has not been elucidated yet. In …

Namco: a microbiome explorer

A Dietrich, MS Matchado, M Zwiebel… - Microbial …, 2022 - microbiologyresearch.org
16S rRNA gene profiling is currently the most widely used technique in microbiome research
and allows the study of microbial diversity, taxonomic profiling, phylogenetics, functional and …