Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …

Abdominal aortic aneurysm (AAA) is a common disease with substantial heritability. In this
study, we performed a genome-wide association meta-analysis from 14 discovery cohorts …

An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a
multifactorial disease, and genetic and environmental factors play a part; smoking, male sex …

Rationale: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and
environmental risk factors. Together, 6 previously identified risk loci only explain a small …

Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Background Abdominal aortic aneurysm (AAA) is the full thickness dilation of the abdominal
aorta. However, few effective medical therapies are available. Thus, elucidating the …

Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein that belongs to
the uncoupling protein family and plays an important role in lowering mitochondrial …

A key aspect of genomic medicine is to make individualized clinical decisions from personal
genomes. We developed a machine-learning framework to integrate personal genomes and …

Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …