Head and neck squamous-cell carcinoma (HNSCC) is the sixth most common cancer
worldwide and, disappointingly, survival rates are not improving. Moreover, HNSCC has a …

There is a saying,“Eyes are the windows to the soul”. In much the same vein, blood, since it
flows through the entire body, can be considered the window to the physical condition of the …

The rising cost of health care is one of the world's most important problems. Accordingly,
predicting such costs with accuracy is a significant first step in addressing this problem …

Background: Protein expression profiling for differences indicative of early cancer has
promise for improving diagnostics. This report describes the first stage of a National Cancer …

In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …

Alterations in proteins abundance, structure, or function, act as useful indicators of
pathological abnormalities prior to development of clinical symptoms and as such are often …

Purpose: We recently showed that protein expression profiling of serum using surface-
enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) has …

Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, or surface-
enhanced laser desorption/ionization ProteinChip® technology, has been widely used in …

Background Currently, no satisfactory biomarkers are available to screen for lung cancer.
Surface-Enhanced Laser Desorption/ionization Time-of-Flight Mass Spectrometry …

Proteomic profiling of serum is an emerging technique to identify new biomarkers indicative
of disease severity and progression. The objective of our study was to assess the use of …