Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …

Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

Animal models provide preclinical tools to investigate the causal role of genetic mutations
and environmental factors in the etiology of autism spectrum disorder (ASD). Knockout and …

Background Viloxazine was historically described as a norepinephrine reuptake inhibitor
(NRI). Since NRIs have previously demonstrated efficacy in attention deficit/hyperactivity …

Thousands of people suffer from nausea with pregnancy each year. Nausea can be
alleviated with cannabidiol (CBD), a primary component of cannabis that is widely available …

HT2Rs have a different genomic organization from other 5-HT2Rs. 5HT2CR undergoes post-
transcriptional pre-mRNA editing generating diversity among RNA transcripts. Selective post …

Autism spectrum disorders (ASDs) are a spectrum of neurodevelopmental disorders
characterized by impaired social interaction and communication, as well as stereotyped and …

Abstract Serotonin (5-HT) is known to play a critical role in regulation of essential neural
processes, whereas more recent research highlights serotonin's modulatory effects on …

The microbiota-gut-brain axis, which refers to the bidirectional communication pathway
between gut bacteria and the central nervous system, has a profound effect on important …

Cognitive impairment affects up to 80% of patients with Parkinson's disease (PD) and is
associated with poor quality of life. PD cognitive dysfunction includes poor working memory …