Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19
F De Virgiliis, S Di Giovanni - Nature Reviews Neurology, 2020 - nature.com
COVID-19 is an infectious disease caused by the coronavirus SARS-CoV-2, which was first
reported in Wuhan, China, in December 2019 and has caused a global pandemic. Acute …
reported in Wuhan, China, in December 2019 and has caused a global pandemic. Acute …
Mechanisms underlying the neuronal-based symptoms of allergy
BJ Undem, T Taylor-Clark - Journal of Allergy and Clinical Immunology, 2014 - Elsevier
Persons with allergies present with symptoms that often are the result of alterations in the
nervous system. Neuronally based symptoms depend on the organ in which the allergic …
nervous system. Neuronally based symptoms depend on the organ in which the allergic …
Eosinophil extracellular traps drive asthma progression through neuro-immune signals
Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li… - Nature Cell …, 2021 - nature.com
Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence
showing that chromatin filaments released from neutrophils mediate various diseases, the …
showing that chromatin filaments released from neutrophils mediate various diseases, the …
Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice
Host resistance to Mycobacterium tuberculos is (Mtb) infection requires the activities of
multiple leukocyte subsets, yet the roles of the different innate effector cells during …
multiple leukocyte subsets, yet the roles of the different innate effector cells during …
Eosinophils increase airway sensory nerve density in mice and in human asthma
MG Drake, GD Scott, ED Blum, KM Lebold… - Science translational …, 2018 - science.org
In asthma, airway nerve dysfunction leads to excessive bronchoconstriction and cough. It is
well established that eosinophils alter nerve function and that airway eosinophilia is present …
well established that eosinophils alter nerve function and that airway eosinophilia is present …
Human eosinophil major basic protein is an endogenous allosteric antagonist at the inhibitory muscarinic M2 receptor.
The effect of human eosinophil major basic protein (MBP) as well as other eosinophil
proteins, on binding of [3H] N-methyl-scopolamine ([3H] NMS: 1 x 10 (-10) M) to muscarinic …
proteins, on binding of [3H] N-methyl-scopolamine ([3H] NMS: 1 x 10 (-10) M) to muscarinic …
Muscarinic receptors and control of airway smooth muscle
Contraction of airway smooth muscle is mediated by M3 muscarinic receptors on the airway
smooth muscle. However, there is no evidence suggesting that hyperresponsiveness results …
smooth muscle. However, there is no evidence suggesting that hyperresponsiveness results …
Muscarinic acetylcholine receptors and airway diseases
FR Coulson, AD Fryer - Pharmacology & therapeutics, 2003 - Elsevier
Parasympathetic nerves provide the dominant autonomic innervation of the airways.
Release of acetylcholine from parasympathetic nerves activates postjunctional muscarinic …
Release of acetylcholine from parasympathetic nerves activates postjunctional muscarinic …
The pathogenesis of chronic obstructivepulmonary disease of horses
NE Robinson, FJ Derksen, MA Olszewski… - British Veterinary …, 1996 - Elsevier
Present evidence suggests that chronic obstructive pulmonary disease (COPD) of horses is
a delayed hypersensitivity response to inhaled antigens, particularly the thermophilic …
a delayed hypersensitivity response to inhaled antigens, particularly the thermophilic …
Eosinophil and airway nerve interactions in asthma
MG Drake, KM Lebold, QR Roth-Carter… - Journal of leukocyte …, 2018 - academic.oup.com
Airway eosinophils are increased in asthma and are especially abundant around airway
nerves. Nerves control bronchoconstiction and in asthma, airway hyperreactivity (where …
nerves. Nerves control bronchoconstiction and in asthma, airway hyperreactivity (where …