Cannabis, the Endocannabinoid System and Immunity—the Journey from the Bedside to the Bench and Back

O Almogi-Hazan, R Or - International journal of molecular sciences, 2020 - mdpi.com
The Cannabis plant contains numerous components, including cannabinoids and other
active molecules. The phyto-cannabinoid activity is mediated by the endocannabinoid …

Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol

P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

Cannabinoid treatment for autism: a proof-of-concept randomized trial

A Aran, M Harel, H Cassuto, L Polyansky, A Schnapp… - Molecular autism, 2021 - Springer
Background Endocannabinoid dysfunction in animal models of autism spectrum disorder
(ASD) and accumulating, albeit anecdotal, evidence for efficacy in humans motivated this …

The endocannabinoidome as a substrate for noneuphoric phytocannabinoid action and gut microbiome dysfunction in neuropsychiatric disorders

V Di Marzo - Dialogues in clinical neuroscience, 2020 - Taylor & Francis
The endocannabinoid (eCB) system encompasses the eCBs anandamide and 2-
arachidonoylglycerol, their anabolic/catabolic enzymes, and the cannabinoid CB1 and CB2 …

Cannabidivarin treatment ameliorates autism-like behaviors and restores hippocampal endocannabinoid system and glia alterations induced by prenatal valproic acid …

E Zamberletti, M Gabaglio… - Frontiers in cellular …, 2019 - frontiersin.org
Autism spectrum disorder (ASD) is a developmental condition whose primary features
include social communication and interaction impairments with restricted or repetitive motor …

[HTML][HTML] A systematic review of cannabidiol trials in neurodevelopmental disorders

NF Parrella, AT Hill, PG Enticott, P Barhoun… - Pharmacology …, 2023 - Elsevier
Cannabis-derived compounds, such as cannabidiol (CBD) and delta-9-trans-
tetrahydrocannabinol (THC), are increasingly prescribed for a range of clinical indications …

Biomarkers in autism spectrum disorders: Current progress

L Shen, XK Liu, H Zhang, J Lin, C Feng, J Iqbal - Clinica Chimica Acta, 2020 - Elsevier
Autism spectrum disorder (ASD) refers to a group of complex neurodevelopmental disorders
characterized by social interaction and communication deficits and repetitive and …

[HTML][HTML] Cannabis and cannabinoid use in autism spectrum disorder: a systematic review

EA Silva Junior, WMB Medeiros, N Torro… - Trends in psychiatry …, 2021 - SciELO Brasil
Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder
characterized by persistent deficits in social communication and social interaction …

Intestinal barrier dysfunction and microbiota–gut–brain axis: Possible implications in the pathogenesis and treatment of autism spectrum disorder

VN Dargenio, C Dargenio, S Castellaneta… - Nutrients, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with
multifactorial etiology, characterized by impairment in two main functional areas:(1) …

The current role of cannabis and cannabinoids in health: A comprehensive review of their therapeutic potential

MP Coelho, P Duarte, M Calado, AJ Almeida, CP Reis… - Life Sciences, 2023 - Elsevier
There has been an increased interest of the scientific community in cannabis and its
constituents for therapeutic purposes. Although it is believed that cannabinoids can be …