BACKGROUND: 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3) is an effective anticancer
agent, and when combined with other agents it shows superior activities. Vitamin B12 has …

An overabundance of MCM7 protein, a component of the minichromosome maintenance
complex that normally initiates DNA replication, has been reported to cause different types of …

Calcitriol, the active form of vitamin D, is known for its anticancer properties including
induction of apoptosis as well as the inhibition of angiogenesis and metastasis …

Osteosarcoma is the most common type of primary bone tumor, and novel therapeutic
approaches for this disease are urgently required. To identify effective agents, we screened …

Besides its well‐known benefits on human health, calcitriol, the hormonally active form of
vitamin D3, has been being evaluated in clinical trials as an anticancer agent. However …

SAMP8 mice exhibit multiple metabolic characteristics associated with age, and it is a
suitable candidate for researching aging associated metabolic dysfunction. Objectives We …

Endometrial cancer is the most common cancer of the female reproductive system.
Combination treatment with specific agents has been widely used as a targeted therapy for …

Background The pathophysiology of neurodegenerative diseases (NDDs) is closely
associated with cellular oxidative stress which can result in the accumulation of toxic …

Objectives Vitamin D is very important for calcium and mineral metabolism, and many
hypotheses appear to link sunlight exposure with cancer risk and prognosis. As many …

Neurodevelopmental disorders, including autism spectrum disorders, have a complex
biological and medical basis involving diverse genetic risk and myriad environmental …