Vitamin B12 enhances the antitumor activity of 1, 25-dihydroxyvitamin d 3 via activation of caspases and targeting actin cytoskeleton
BACKGROUND: 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3) is an effective anticancer
agent, and when combined with other agents it shows superior activities. Vitamin B12 has …
agent, and when combined with other agents it shows superior activities. Vitamin B12 has …
In silico investigation of the role of vitamins in cancer therapy through inhibition of MCM7 oncoprotein
An overabundance of MCM7 protein, a component of the minichromosome maintenance
complex that normally initiates DNA replication, has been reported to cause different types of …
complex that normally initiates DNA replication, has been reported to cause different types of …
High concentration calcitriol induces endoplasmic reticulum stress related gene profile in breast cancer cells
Calcitriol, the active form of vitamin D, is known for its anticancer properties including
induction of apoptosis as well as the inhibition of angiogenesis and metastasis …
induction of apoptosis as well as the inhibition of angiogenesis and metastasis …
Calcitriol exerts an anti‐tumor effect in osteosarcoma by inducing the endoplasmic reticulum stress response
T Shimizu, WA Kamel, S Yamaguchi‐Iwai… - Cancer …, 2017 - Wiley Online Library
Osteosarcoma is the most common type of primary bone tumor, and novel therapeutic
approaches for this disease are urgently required. To identify effective agents, we screened …
approaches for this disease are urgently required. To identify effective agents, we screened …
High‐dose vitamin D metabolite delivery inhibits breast cancer metastasis
J Liu, J Shen, C Mu, Y Liu, D He, H Luo… - Bioengineering & …, 2022 - Wiley Online Library
Besides its well‐known benefits on human health, calcitriol, the hormonally active form of
vitamin D3, has been being evaluated in clinical trials as an anticancer agent. However …
vitamin D3, has been being evaluated in clinical trials as an anticancer agent. However …
Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice
Y Rui, J Cheng, L Qin, C Shan, J Chang, G Wang… - Experimental …, 2017 - Elsevier
SAMP8 mice exhibit multiple metabolic characteristics associated with age, and it is a
suitable candidate for researching aging associated metabolic dysfunction. Objectives We …
suitable candidate for researching aging associated metabolic dysfunction. Objectives We …
[HTML][HTML] Perifosine and vitamin D combination induces apoptotic and non-apoptotic cell death in endometrial cancer cells
Endometrial cancer is the most common cancer of the female reproductive system.
Combination treatment with specific agents has been widely used as a targeted therapy for …
Combination treatment with specific agents has been widely used as a targeted therapy for …
1, 25-(OH)2D3 protects against ER stress and miRNA dysregulation in Mus musculus neurons
P Jayachandran, L Koshy, PR Sudhakaran, GM Nair… - Genes & Genomics, 2022 - Springer
Background The pathophysiology of neurodegenerative diseases (NDDs) is closely
associated with cellular oxidative stress which can result in the accumulation of toxic …
associated with cellular oxidative stress which can result in the accumulation of toxic …
Evaluation of the potential anticancer activity of different vitamin D metabolites on colorectal and breast cancer cell lines
Objectives Vitamin D is very important for calcium and mineral metabolism, and many
hypotheses appear to link sunlight exposure with cancer risk and prognosis. As many …
hypotheses appear to link sunlight exposure with cancer risk and prognosis. As many …
[PDF][PDF] Autism is an acquired cellular detoxification deficiency syndrome with heterogeneous genetic predisposition
J Lyons-Weiler - Autism Open Access, 2018 - researchgate.net
Neurodevelopmental disorders, including autism spectrum disorders, have a complex
biological and medical basis involving diverse genetic risk and myriad environmental …
biological and medical basis involving diverse genetic risk and myriad environmental …