A review of hydrogen sulfide (H2S) donors: Chemistry and potential therapeutic applications

CR Powell, KM Dillon, JB Matson - Biochemical pharmacology, 2018 - Elsevier
Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter

JL Wallace, R Wang - Nature reviews Drug discovery, 2015 - nature.com
Hydrogen sulfide (H2S) has become recognized as an important signalling molecule
throughout the body, contributing to many physiological and pathological processes. In …

Diet as a trigger or therapy for inflammatory bowel diseases

JD Lewis, MT Abreu - Gastroenterology, 2017 - Elsevier
The most common question asked by patients with inflammatory bowel disease (IBD)
is,“Doctor, what should I eat?” Findings from epidemiology studies have indicated that diets …

[HTML][HTML] Hydrogen sulfide promotes Tet1-and Tet2-mediated Foxp3 demethylation to drive regulatory T cell differentiation and maintain immune homeostasis

R Yang, C Qu, Y Zhou, JE Konkel, S Shi, Y Liu, C Chen… - Immunity, 2015 - cell.com
Regulatory T (Treg) cells are essential for maintenance of immune homeostasis. Here we
found that hydrogen sulfide (H 2 S) was required for Foxp3+ Treg cell differentiation and …

Hydrogen sulfide and cell signaling

L Li, P Rose, PK Moore - Annual review of pharmacology and …, 2011 - annualreviews.org
Hydrogen sulfide (H2S) is a gaseous mediator synthesized from cysteine by cystathionine γ
lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments using …

Progress and perspective on hydrogen sulfide donors and their biomedical applications

ZL Song, L Zhao, T Ma, A Osama… - Medicinal Research …, 2022 - Wiley Online Library
Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

[HTML][HTML] Hydrogen sulfide in physiology and diseases of the digestive tract

SB Singh, HC Lin - Microorganisms, 2015 - mdpi.com
Hydrogen sulfide (H2S) is a Janus-faced molecule. On one hand, several toxic functions
have been attributed to H2S and exposure to high levels of this gas is extremely hazardous …

Hydrogen sulfide as a gasotransmitter

MM Gadalla, SH Snyder - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 10.1111/j. 1471‐4159.2010. 06580. x Abstract Nitric oxide (NO) and
carbon monoxide (CO) are well established as messenger molecules throughout the body …

Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

K Kashfi, KR Olson - Biochemical pharmacology, 2013 - Elsevier
Hydrogen sulfide, H2S, is a colorless gas with a strong odor that until recently was only
considered to be a toxic environmental pollutant with little or no physiological significance …