The KDM5 family of histone demethylases removes the H3K4 tri-methylation (H3K4me3)
mark frequently found at promoter regions of actively transcribed genes and is therefore …

Background/Aims: Autophagy is a cellular degradation process for the recycling of damaged
or superfluous intracellular compartments to provide an alternative energy source during …

Abstract Ginsenoside Rh2 (GRh2) has been reported to have therapeutic effects on some
types of cancer, but its effect on prostatic cancer has not been extensively evaluated. Here …

Prostate cancer (PC) is a prevalent cancer in aged men. Curcumin is an active ingredient
that has been extracted from the rhizome of the plant Curcuma longa. Recently, a potential …

Background/Aims: Notch signaling pathway regulates cancer cell growth. RBPJ is a key
transcription factor downstream of Notch receptor activation, whereas the role of RBPJ in …

Norcantharidin (NCTD) has an anticancer potential to allow it to be used in the treatment of
some malignant cancers. However, whether NCTD may have similar anticancer effects on …

Increased expression of pituitary tumor-transforming gene 1 (PTTG1) occurs during mitosis-
related sister chromatid segregation, and characterizes various tumor cells, including …

Pituitary tumor‐transforming gene 1 (PTTG1) is a regulator of chromosome stability. PTTG1
overexpression had been associated with tumor aggressiveness in several cancer types. To …

Many cervical cancer (CC) patients experience early cancer metastasis, resulting in poor
therapeutic outcome after resection of primary cancer. Hence, there is a compelling …

Simple Summary Seminoma represents one of the most common neoplasms in Caucasian
males between 15 and 40 years old. The molecular pathways underlying its clinical …