Structural changes involving tissue remodelling and fibrosis are major features of many
pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and …

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

In the lungs, fibrosis is a growing clinical problem that results in shortness of breath and can
end up in respiratory failure. Even though the main fibrotic disease affecting the lung is …

Fibrosis refers to excessive build‐up of scar tissue and extracellular matrix components in
different organs. In recent years, it has been revealed that different cytokines and …

Idiopathic pulmonary fibrosis (IPF) is a debilitating and fatal condition that causes severe
scarring of the lungs. While the pathogenesis of IPF continues to be extensively studied and …

Three recent clinical trials on the pharmacologic treatment of idiopathic pulmonary fibrosis
(IPF) mark a new chapter in the management of patients suffering from this very severe …

Significance: Idiopathic pulmonary fibrosis (IPF) is a progressive age-related lung disease
with a median survival of only 3 years after diagnosis. The pathogenic mechanisms behind …

Aims: Oxidants have been implicated in the pathophysiology of idiopathic pulmonary fibrosis
(IPF), especially in myofibroblastic differentiation. We aimed at testing the hypothesis that …

Background Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal illness whose
pathogenesis remains poorly understood. Recent evidence suggests oxidative stress as a …