Muscle fibres have different properties with respect to force, contraction speed, endurance,
oxidative/glycolytic capacity etc. Although adult muscle fibres are normally post‐mitotic with …

It has been well-established that the age-related loss of muscle mass and strength, or
sarcopenia, impairs skeletal muscle function and reduces functional performance at a more …

Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) acutely reduce
skeletal muscle strength and result in long-term loss of functional capacity. Objectives: To …

Key points• Elderly individuals require a prolonged recovery phase in order to return to initial
muscle mass levels following short‐term immobilisation.• The cellular mechanisms …

This review provides evidence for the hypothesis that electrostimulation strength training
(EST) increases the force of a maximal voluntary contraction (MVC) through neural …

Background: In chronic heart failure (CHF), cardiac cachexia is often associated with the
terminal stage of this disease. In animal studies it has been demonstrated that myostatin, a …

Skeletal muscle satellite cells (SCs) have been shown to be instrumental in the muscle
adaptive response to exercise. The present study determines age-related differences in SC …

Klotho is a powerful longevity protein that has been linked to the prevention of muscle
atrophy, osteopenia, and cardiovascular disease. Similar anti-aging effects have also been …

Cytokine interleukin-6 (IL-6) is an essential regulator of satellite cell-mediated hypertrophic
muscle growth through the transcription factor signal transducer and activator of transcription …

Progressive skeletal muscle wasting in cancer cachexia involves a process of dysregulated
protein synthesis and breakdown. This catabolism may be the result of mal‐nutrition, and an …