[HTML][HTML] Acute kidney injury in septic patients treated by selected nephrotoxic antibiotic agents—pathophysiology and biomarkers—a review

N Petejova, A Martinek, J Zadrazil, M Kanova… - International journal of …, 2020 - mdpi.com
Acute kidney injury is a common complication in critically ill patients with sepsis and/or
septic shock. Further, some essential antimicrobial treatment drugs are themselves …

[HTML][HTML] Epigenetic mechanisms involved in cisplatin-induced nephrotoxicity: an update

P Loren, N Saavedra, K Saavedra, T Zambrano… - Pharmaceuticals, 2021 - mdpi.com
Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its
various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic …

[HTML][HTML] Dysregulated MicroRNAs as biomarkers or therapeutic targets in cisplatin-induced nephrotoxicity: a systematic review

N de Godoy Torso, JKN Pereira, MB Visacri… - International Journal of …, 2021 - mdpi.com
The purpose of this systematic review was to map out and summarize scientific evidence on
dysregulated microRNAs (miRNAs) that can be possible biomarkers or therapeutic targets …

[HTML][HTML] Radix Rehmannia Glutinosa inhibits the development of renal fibrosis by regulating miR-122-5p/PKM axis

X Liu, H Xu, Y Zang, W Liu, X Sun - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: It is acknowledged that Radix Rehmanniae Praeparata (RR) can regulate
hormone metabolism, reduce blood glucose, resist aging, help to sedate patients and …

Clofibrate, a peroxisome proliferator–activated receptor-alpha (PPARα) agonist, and its molecular mechanisms of action against sodium fluoride–induced toxicity

AA Oyagbemi, OA Adejumobi, TA Jarikre… - … Trace Element Research, 2022 - Springer
Sodium fluoride (NaF) is one of the neglected environmental pollutants. It is ubiquitously
found in the soil, water, and environment. Interestingly, fluoride has been extensively utilized …

MicroRNAs mediate the anti-tumor and protective effects of ginsenosides

M Ashrafizadeh, Z Ahmadi… - Nutrition and …, 2020 - Taylor & Francis
MicroRNAs (miRs (, as short non-coding RNAs, regulate important biological processes and
mainly are associated with regulation of gene expression. The miRs are beneficial targets …

顺铂诱导急性肾损伤研究进展

庞硕, 孔德阳 - 肾脏病与透析肾移植杂志, 2020 - njcndt.com
顺铂(CDDP) 是临床常用化疗药物, 急性肾损伤(AKI) 是CDDP 治疗的严重并发症.
临床实施CDDP 抗癌限制肾毒性方案有赖于对CDDP 诱导AKI (CDDP AKI) 病理生理学认知 …

[HTML][HTML] 18F-FDG PET/MRI Imaging in a Preclinical Rat Model of Cardiorenal Syndrome—An Exploratory Study

DM Furcea, L Agrigoroaie, CT Mihai… - International Journal of …, 2022 - mdpi.com
Cardiorenal syndrome (CRS) denotes the bidirectional interaction of chronic kidney disease
and heart failure with an adverse prognosis but with a limited understanding of its …

MicroRNAs in toxic acute kidney injury: Systematic scoping review of the current status

F Shihana, ML Barron, F Mohamed… - Pharmacology …, 2021 - Wiley Online Library
Acute kidney injury induced by nephrotoxic agents is common, increasing in incidence and
associated with considerable morbidity and mortality in developing countries. MicroRNAs …

Exploration of small RNA biomarkers for testicular injury in the serum exosomes of rats

R Kawata, T Kagawa, Y Koya, H Kajiyama, S Oda… - Toxicology, 2020 - Elsevier
Testicular injury is often observed in drug development. Serum hormones are usually used
as noninvasive biomarkers for testicular injury; however, their sensitivities are low …