Self‐assembling peptide nanofiber hydrogels in tissue engineering and regenerative medicine: progress, design guidelines, and applications

S Koutsopoulos - … of Biomedical Materials Research Part A, 2016 - Wiley Online Library
Until the mid‐1980s, mainly biologists were conducting peptide research. This changed with
discoveries that opened new paths of research involving the use of peptides in …

Synthetic peptide hydrogels as 3D scaffolds for tissue engineering

X Ding, H Zhao, Y Li, AL Lee, Z Li, M Fu, C Li… - Advanced Drug Delivery …, 2020 - Elsevier
The regeneration of tissues and organs poses an immense challenge due to the extreme
complexity in the research work involved. Despite the tissue engineering approach being …

Construction and application of textile-based tissue engineering scaffolds: a review

Y Jiao, C Li, L Liu, F Wang, X Liu, J Mao… - Biomaterials Science, 2020 - pubs.rsc.org
Tissue engineering (TE) provides a practicable method for tissue and organ repair or
substitution. As the most important component of TE, a scaffold plays a critical role in …

Synergistic antitumor potency of a self-assembling peptide hydrogel for the local co-delivery of doxorubicin and curcumin in the treatment of head and neck cancer

C Karavasili, DA Andreadis, OL Katsamenis… - Molecular …, 2019 - ACS Publications
Combination therapy has been conferred with manifold assets leveraging the synergy of
different agents to achieve a sufficient therapeutic outcome with lower administered drug …

A review of treatments for non-compressible torso hemorrhage (NCTH) and internal bleeding

C Hong, BD Olsen, PT Hammond - Biomaterials, 2022 - Elsevier
Non-compressible torso hemorrhage (NCTH) is associated with significant mortality in
preventable deaths, both in the field and in civilian settings. Current management strategies …

Biomimetic scaffolds for tendon tissue regeneration

L Huang, L Chen, H Chen, M Wang, L Jin, S Zhou… - Biomimetics, 2023 - mdpi.com
Tendon tissue connects muscle to bone and plays crucial roles in stress transfer. Tendon
injury remains a significant clinical challenge due to its complicated biological structure and …

Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications

R Wang, Z Wang, Y Guo, H Li… - Journal of Biomaterials …, 2019 - Taylor & Francis
RADA16 (RADARADARADARADA) is an amphiphilic polypeptide composed of 16 amino
acids, which is composed of alternating positively charged arginine (R), hydrophobic …

Bio-instructive materials for musculoskeletal regeneration

T Gonzalez-Fernandez, P Sikorski, JK Leach - Acta biomaterialia, 2019 - Elsevier
The prevalence and cost of disorders affecting the musculoskeletal system are predicted to
rise significantly in the coming years due to the aging global population and the increase of …

Self-assembling peptide RADA16: a promising scaffold for tissue engineering and regenerative medicine

X Yao, Y Hu, M Lin, K Peng, P Wang, Y Gao, X Gao… - …, 2023 - Taylor & Francis
RADA16 is a peptide-based biomaterial whose acidic aqueous solution spontaneously
forms an extracellular matrix-like 3D structure within seconds upon contact with …

Modified silk fibroin scaffolds with collagen/decellularized pulp for bone tissue engineering in cleft palate: morphological structures and biofunctionalities

S Sangkert, J Meesane, S Kamonmattayakul… - Materials Science and …, 2016 - Elsevier
Cleft palate is a congenital malformation that generates a maxillofacial bone defect around
the mouth area. The creation of performance scaffolds for bone tissue engineering in cleft …