Background The healing of periapical lesions after root canal treatment (RCT) is not the
result of the curative action of the treatment. The process of healing begins with …

Endodontics has gained emphasis in the scientific community in recent years due to the
increase in clinical and in animal models studies focused on endodontic medicine, which …

Apical periodontitis is an oral common inflammatory disease initiated by infection of pulp
chamber and is characterized by destruction and resorption of the periapical bone. As a …

Introduction This study evaluated whether apical periodontitis (AP) in a single tooth or in
multiple teeth affected serum levels of inflammatory mediators and influenced blood …

Endodontic medicine, which addresses the bidirectional relationship between endodontic
infections and systemic diseases, has gained prominence in the field of endodontics. There …

Background: Little evidence is available regarding the effects of long‐term periodontal
infection on diabetes mellitus (DM) control. The aim of this retrospective cohort study is to …

Aim To verify the effects of melatonin supplementation on insulin sensitivity, plasma
concentrations of inflammatory cytokines, insulin signalling and inflammatory pathways in …

Objectives The effects of apical periodontitis (AP) and periodontal disease (PD) on organ
weights in rats with diabetes mellitus (DM) were evaluated. Design Eighty male rats (Rattus …

Objectives The aim of this study was to determine whether the presence of single or multiple
apical periodontitis (AP) alters blood cell counts and cytokine production. Material and …

Introduction Our previous studies have shown that periapical lesions (PLs) in rats cause
systemic disorders such as increased tumor necrosis factor-α plasma levels, insulin …