Breast cancer screening modalities, recommendations, and novel imaging techniques

S Nielsen, AK Narayan - Surgical Clinics, 2023 - surgical.theclinics.com
Breast cancer remains the second leading cause of cancer death for women in the United
States. 1 In the United States in 2022, the American Cancer Society (ACS) estimates that …

Predictors of treatment refusal in patients with colorectal cancer: A systematic review

Y Moodley, K Govender, J van Wyk, S Reddy… - Seminars in …, 2022 - Elsevier
This systematic review was conducted to investigate predictors of treatment refusal in
colorectal cancer (CRC) patients. An understanding of these predictors would inform …

Where are the inequalities in colorectal cancer care in a country with universal healthcare? A systematic review and narrative synthesis

BA Pickwell-Smith, K Spencer, MH Sadeghi… - BMJ open, 2024 - bmjopen.bmj.com
Objective Patients diagnosed with colorectal cancer living in more deprived areas
experience worse survival than those in more affluent areas. Those living in more deprived …

Oncologist-reported barriers and facilitators to enrolling patients in optimization trials that test less intense cancer treatment

GB Rocque, C Andrews, VM Lawhon, R Frazier… - JCO Oncology …, 2023 - ascopubs.org
PURPOSE: As outcomes improve in early-stage breast cancer, clinical trials are undergoing
a paradigm shift from intensification trials (more therapy) to improve survival to optimization …

Physicians' Hierarchy of Tumor Biomarkers for Optimizing Chemotherapy in Breast Cancer Care

HH Thannickal, N Eltoum, NL Henderson… - The …, 2024 - academic.oup.com
Background Tumor biomarkers are regularly used to guide breast cancer treatment and
clinical trial enrollment. However, there remains a lack of knowledge regarding physicians' …

Hit it hard: qualitative patient perspectives on the optimisation of immune checkpoint inhibition

S Merrick, HL Rush, S Daniels, A Fielding… - British Journal of …, 2024 - nature.com
Background Immune checkpoint inhibitors have transformed the treatment landscape of
many cancers, including melanoma and renal cell carcinoma (RCC). Randomised trials are …

Leveraging the potential for deintensification in cancer care

JA Soon, F Franchini, MJ IJzerman, GA McArthur - Nature cancer, 2024 - nature.com
Evidence-based reductions in cancer treatment that still preserve outcomes can result in an
improved quality of life for patients and optimized healthcare resourcing. Using melanoma …

De-escalating breast cancer therapy

MA Varsanik, SP Shubeck - Surgical Clinics, 2023 - surgical.theclinics.com
Patients with breast cancer, including those with early-stage disease, have historically been
subject to invasive surgical procedures, medical therapies, and radiation therapy. However …

[HTML][HTML] “Oh when's your treatment ending?”“Never!” The unmet needs of cancer patients treated with immuno-, biological and precision therapies: a qualitative …

L Crowe, MC Brown, J Lecouturier, A Greystoke… - European Journal of …, 2024 - Elsevier
Purpose To explore the unmet supportive care needs of patients with advanced cancer
receiving immune-biological and precision (IBP) therapies. Methods We conducted semi …

“Clinical trials are space travel”: Factors of psychological response to recurrence among oncologists enrolling patients in treatment optimization trials

NL Henderson, C Andrews, SA Ingram… - Cancer …, 2023 - Wiley Online Library
Background Cancer recurrence after treatment is a concern for patients and oncologists
alike. The movement towards treatment optimization, with trials testing less than the current …