Drug release from liquisolid systems: speed it up, slow it down
A Nokhodchi, CM Hentzschel… - Expert opinion on drug …, 2011 - Taylor & Francis
Introduction: Today, the properties of many new chemical entities have shifted towards
higher molecular weights and this in turn increases the lipophilicity hence decreasing …
higher molecular weights and this in turn increases the lipophilicity hence decreasing …
[PDF][PDF] Enhancement of the Solubility of Poorly Water Soluble Drugs through Solid Dispersion: A Comprehensive Review.
G Singh, L Kaur, GD Gupta… - Indian Journal of …, 2017 - researchgate.net
Solubility is an important determinant in drug liberation and hence drug absorption, which
plays a key role in oral bioavailability of formulations. The dissolution rate of a drug directly …
plays a key role in oral bioavailability of formulations. The dissolution rate of a drug directly …
Development of azithromycin–PLGA nanoparticles: Physicochemical characterization and antibacterial effect against Salmonella typhi
The objective of the present research was to formulate poly (lactide-co-glycolide)
nanoparticles loaded with azithromycin with appropriate physicochemical properties and …
nanoparticles loaded with azithromycin with appropriate physicochemical properties and …
[HTML][HTML] Pharmaceutical cocrystal of piroxicam: design, formulation and evaluation
P Panzade, G Shendarkar, S Shaikh… - Advanced …, 2017 - ncbi.nlm.nih.gov
Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid
sate properties of drug substances like solubility and dissolution. The objective of the …
sate properties of drug substances like solubility and dissolution. The objective of the …
Piroxicam nanoparticles for ocular delivery: physicochemical characterization and implementation in endotoxin-induced uveitis
K Adibkia, MRS Shadbad, A Nokhodchi… - Journal of drug …, 2007 - Taylor & Francis
To investigate the anti-inflammatory impacts of piroxicam nanosuspension, in the current
investigation, piroxicam: Eudragit® RS100 nanoformulations were used to control …
investigation, piroxicam: Eudragit® RS100 nanoformulations were used to control …
Biopharmaceutical classification of drugs using intrinsic dissolution rate (IDR) and rat intestinal permeability
P Zakeri-Milani, M Barzegar-Jalali, M Azimi… - European journal of …, 2009 - Elsevier
The solubility and dissolution rate of active ingredients are of major importance in
preformulation studies of pharmaceutical dosage forms. In the present study, passively …
preformulation studies of pharmaceutical dosage forms. In the present study, passively …
Physicochemical and anti-bacterial performance characterization of clarithromycin nanoparticles as colloidal drug delivery system
The objective of the present study was to prepare clarithromycin (CLR) loaded
biodegradable nanoparticles (NPS), with a view to investigate its physicochemical …
biodegradable nanoparticles (NPS), with a view to investigate its physicochemical …
Suitability of various excipients as carrier and coating materials for liquisolid compacts
CM Hentzschel, A Sakmann… - Drug development and …, 2011 - Taylor & Francis
Context: The liquisolid technology is a promising technique for the release enhancement of
poorly soluble drugs. With this approach, liquids such as solutions or suspensions of poorly …
poorly soluble drugs. With this approach, liquids such as solutions or suspensions of poorly …
Cogrinding as an approach to enhance dissolution rate of a poorly water-soluble drug (gliclazide)
M Barzegar-Jalali, H Valizadeh, MRS Shadbad… - Powder Technology, 2010 - Elsevier
Gliclazide is practically insoluble in water. In order to improve the drug dissolution rate,
cogrinding method was used as an approach to prepare gliclazide coground/solid …
cogrinding method was used as an approach to prepare gliclazide coground/solid …
Comparison of physicochemical characteristics and drug release of diclofenac sodium–eudragit® RS100 nanoparticles and solid dispersions
M Barzegar-Jalali, M Alaei-Beirami, Y Javadzadeh… - Powder Technology, 2012 - Elsevier
The aim of the present study was to formulate and characterize diclofenac sodium (DNa)–
eudragit® RS100 nanoparticles and solid dispersions. The conventional double-emulsion …
eudragit® RS100 nanoparticles and solid dispersions. The conventional double-emulsion …