Introduction: Today, the properties of many new chemical entities have shifted towards
higher molecular weights and this in turn increases the lipophilicity hence decreasing …

Solubility is an important determinant in drug liberation and hence drug absorption, which
plays a key role in oral bioavailability of formulations. The dissolution rate of a drug directly …

The objective of the present research was to formulate poly (lactide-co-glycolide)
nanoparticles loaded with azithromycin with appropriate physicochemical properties and …

Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid
sate properties of drug substances like solubility and dissolution. The objective of the …

To investigate the anti-inflammatory impacts of piroxicam nanosuspension, in the current
investigation, piroxicam: Eudragit® RS100 nanoformulations were used to control …

The solubility and dissolution rate of active ingredients are of major importance in
preformulation studies of pharmaceutical dosage forms. In the present study, passively …

The objective of the present study was to prepare clarithromycin (CLR) loaded
biodegradable nanoparticles (NPS), with a view to investigate its physicochemical …

Context: The liquisolid technology is a promising technique for the release enhancement of
poorly soluble drugs. With this approach, liquids such as solutions or suspensions of poorly …

Gliclazide is practically insoluble in water. In order to improve the drug dissolution rate,
cogrinding method was used as an approach to prepare gliclazide coground/solid …

The aim of the present study was to formulate and characterize diclofenac sodium (DNa)–
eudragit® RS100 nanoparticles and solid dispersions. The conventional double-emulsion …