Covering: 2010 to 2022 Heterologous expression of natural product biosynthetic gene
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …

Covering: up to August 2023Terpenoids, which are widely distributed in animals, plants, and
microorganisms, are a large group of natural products with diverse structures and various …

Abstract Tandem Diels–Alder reactions are frequently used in the construction of polycyclic
ring systems in complex organic compounds. Unlike the many Diels− Alderases (DAases) …

To date little is known about the genetic background that drives the production and
diversification of secondary metabolites in the Hypoxylaceae. With the recent availability of …

The sesquiterpene-tropolones belong to a distinctive structural class of meroterpene natural
products with impressive biological activities, including anticancer, antifungal, antimalarial …

Fungal hybrid terpenoid saccharides constitute a new and growing family of natural products
with significant biomedical and agricultural activities. One representative family is the …

Conspectus The Diels–Alder reaction is well known as a concerted [4+ 2] cycloaddition
governed by the Woodward–Hoffmann rules. Since Prof. Otto Diels and his student Kurt …

Filamentous fungi produce a very wide range of complex and often bioactive metabolites,
demonstrating their inherent ability as hosts of complex biosynthetic pathways. Recent …

Covering: 2015 to 2022 Fungal terpenoids are of large structural diversity and often exhibit
interesting biological activities. Recent work has focused on two main aspects:(1) the …

Covering the period 1965–2024 Total synthesis has been defined as the art and science of
making the molecules of living Nature in the laboratory, and by extension, their analogues …