Small molecule-based core and shell cross-linked nanoassemblies: from self-assembly and programmed disassembly to biological applications

S Santra, MR Molla - Chemical Communications, 2024 - pubs.rsc.org
Supramolecular assemblies of stimuli-responsive amphiphilic molecules have been of
utmost interest in the broad area of targeted drug delivery applications, owing to their …

Redox-responsive biodegradable dendronized polymers: A side-chain modulation based fabrication of drug delivery vehicles

F Calik, A Degirmenci, R Sanyal, A Sanyal - European Polymer Journal, 2023 - Elsevier
Among various nanomedicine platforms, stimuli-responsive biodegradable polymeric
micelles offer a viable approach to address challenges in cancer therapy. Herein, we report …

Tumor acidity-induced surface charge modulation in covalent nanonetworks for activated cellular uptake: Targeted delivery of anticancer drugs and selective cancer …

S Santra, S Das, A Sengupta, MR Molla - Biomaterials Science, 2023 - pubs.rsc.org
A β-thioester and tertiary amine based covalently cross-linked nanoassembly coined as a
nanonetwork (NN) endowed with dual pH responsive features (tumor acidity induced …

Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid for Application in the Clinic

C Bellini, F Mancin, E Papini, R Tavano - Antioxidants, 2024 - mdpi.com
α-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps
protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect …

Degradable Polymer-Based Nanoassemblies for Precise Targeting and Drug Delivery to Breast Cancer Cells without Affecting Normal Healthy Cells

S Santra, S Das, S Dey, A Sengupta, B Giri… - …, 2024 - ACS Publications
Stimuli-responsive amphiphilic polymers are known to be precursors to forming promising
nanoarchitectonics with tunable properties for application in biomedical sciences. Currently …

Fe-Mediated Self-Assembled Nanodrug for Tumor Microenvironment Activated Synergistic Ferroptosis-Based-Chemodynamic/Chemo Therapy and Magnetic …

Z Xu, L Zhang, M Gong, T Sun, C Zhou… - ACS Materials …, 2024 - ACS Publications
Due to the low drug concentration, glutathione (GSH)-based oxidative stress regulating
system in target tissues, and serious side effects, doxorubicin (DOX) usually shows a …

Thiol–Ene Click Cross-linking of Starch Oleate Films for Enhanced Properties

L Boetje, X Lan, J van Dijken, G Kaastra… - …, 2023 - ACS Publications
Biobased films were synthesized from starch oleate (DS= 2.2) cross-linked with polyethylene
glycol with M n= 2000 and 1000 g· mol–1, and ethylene glycol, all of which were esterified …

Tetranuclear PdII Complexes Containing an Adamantane-Based Tetra-MIC Ligand: Ancillary-Ligand-Dependent Catalytic and Redox Activities

B Mondal, R Naskar, J Bag, S Garai, R Maity - Organometallics, 2024 - ACS Publications
The novel tetra-triazolium salt 1, featuring a tetrasubstituted central adamantane backbone,
is introduced for the synthesis of tetranuclear PdII MIC complexes by quadruple C5–H …

Enzyme-Triggered Degradation of Supramolecularly Cross-Linked Polymersomes of Azobenzene-Based Polyurethane: Cell-Selective Anticancer Drug Release

S Kolay, M Das, A Mondal, A Sengupta, S Bag… - …, 2024 - ACS Publications
Enzyme-responsive self-assembled nanostructures for drug delivery applications have
gained a lot of attention, as enzymes exhibit dysregulation in many disease-associated …

Facile synthesis and polymerization of 1, 4, 5-oxadithiepan-2-one for disulfide-based redox-responsive drug delivery

D Chakraborty, A Sengupta, J Bhattacharyya, J Jacob - Polymer, 2024 - Elsevier
Chemotherapeutic drugs have been shown to be promising for the treatment of tumors,
however, they are associated with several disadvantages including low aqueous solubility …