Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS)

V Ehrlich, W Bil, R Vandebriel, B Granum, M Luijten… - Environmental …, 2023 - Springer
Background Per-and polyfluoroalkyl substances (PFAS) are of public health concern,
because of their ubiquitous and extremely persistent occurrence, and depending on their …

A review on structural mechanisms of protein-persistent organic pollutant (POP) interactions

N Nagar, H Saxena, A Pathak, A Mishra, KM Poluri - Chemosphere, 2023 - Elsevier
With the advent of the industrial revolution, the accumulation of persistent organic pollutants
(POPs) in the environment has become ubiquitous. POPs are halogen-containing organic …

Adsorption, structure, and dynamics of short-and long-chain PFAS molecules in kaolinite: molecular-level insights

N Loganathan, AK Wilson - Environmental Science & Technology, 2022 - ACS Publications
The ubiquitous presence of poly-and perfluoroalkyl substances (PFAS) in different natural
settings poses a serious threat to environmental and human health. Soils and sediments …

The association between prenatal per-and polyfluoroalkyl substance levels and Kawasaki disease among children of up to 4 years of age: A prospective birth cohort of …

H Iwata, S Kobayashi, M Itoh, S Itoh, RM Ketema… - Environment …, 2024 - Elsevier
Kawasaki disease (KD) is common among pediatric patients and is associated with an
increased risk of later cardiovascular complications, though the precise pathophysiology of …

In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per-and polyfluoroalkyl substances (PFAS)

R Dharpure, S Pramanik, A Pradhan - Archives of Toxicology, 2023 - Springer
Transthyretin (TTR) is a homo-tetramer protein involved in the transport of thyroid hormone
(thyroxine; T4) in the plasma and cerebrospinal fluid. Many pollutants have been shown to …

[HTML][HTML] Role of bioavailability and protein binding of four anionic perfluoroalkyl substances in cell-based bioassays for quantitative in vitro to in vivo extrapolations

W Qin, L Henneberger, J Huchthausen, M König… - Environment …, 2023 - Elsevier
Perfluoroalkyl substances (PFAS) are persistent and pose a risk to human health. High
throughput screening (HTS) cell-based bioassays may inform risk assessment of PFAS …

Pre-differentiation exposure of PFOA induced persistent changes in DNA methylation and mitochondrial morphology in human dopaminergic-like neurons

H Zhao, J Xie, S Wu, OF Sánchez, X Zhang… - Environmental …, 2022 - Elsevier
Perfluorooctanoic acid (PFOA) is abundant in environment due to its historical uses in
consumer products and industrial applications. Exposure to low doses of PFOA has been …

Molecular screening and toxicity estimation of 260,000 perfluoroalkyl and polyfluoroalkyl substances (PFASs) through machine learning

TT Lai, D Kuntz, AK Wilson - Journal of Chemical Information and …, 2022 - ACS Publications
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are a class of chemicals widely used
in industrial applications due to their exceptional properties and stability. However, they do …

Toxicological evaluation of TBBPA by common carp (Cyprinus carpio) about the in vivo/vitro disturbance of the AHR pathway

R Wang, C Zhang, X Li, W Sha, Z Xue, Z Zhou… - Science of The Total …, 2023 - Elsevier
Tetrabromobisphenol A (TBBPA) is a widely used plastic additive with high bioaccumulation
potential and toxicity on both humans and wildlife. Currently, research on its ecotoxicity and …

Influence of soil minerals on the adsorption, structure, and dynamics of GenX

CE Schumm, N Loganathan, AK Wilson - ACS ES&T Water, 2023 - ACS Publications
In recent years, there have been increasing initiatives undertaken worldwide to employ
alternative per-and polyfluoroalkyl substances (PFAS) molecules in order to minimize the …