Molecular and structural insights into the life cycle of rubella virus

PK Das, M Kielian - Journal of virology, 2021 - Am Soc Microbiol
Rubella virus (RUBV), a rubivirus, is an airborne human pathogen that generally causes
mild measles-like symptoms in children or adults. However, RUBV infection of pregnant …

Baculovirus-mediated large-scale expression and purification of a polyhistidine-tagged rubella virus capsid protein

M Schmidt, N Tuominen, T Johansson, SA Weiss… - Protein expression and …, 1998 - Elsevier
The capsid protein of rubella virus was produced in baculovirus-infectedSpodoptera
frugiperdainsect cells, with a polyhistidine affinity tag at the carboxy terminus. The RV capsid …

Interactions between rubella virus capsid and host protein p32 are important for virus replication

MD Beatch, JC Everitt, LMJ Law, TC Hobman - Journal of virology, 2005 - Am Soc Microbiol
The distribution and morphology of mitochondria are dramatically affected during infection
with rubella virus (RV). Expression of the capsid, in the absence of other viral proteins, was …

Molecular virology of rubella virus

MH Chen, J Icenogle - Perspectives in medical virology, 2006 - Elsevier
Publisher Summary Rubella virus is a potent, infectious, teratogenic agent that continues to
cause devastating epidemics of congenital rubella syndrome (CRS) in much of the world …

A disulfide-bonded dimer of the core protein of hepatitis C virus is important for virus-like particle production

Y Kushima, T Wakita, M Hijikata - Journal of virology, 2010 - Am Soc Microbiol
Hepatitis C virus (HCV) core protein forms the nucleocapsid of the HCV particle. Although
many functions of core protein have been reported, how the HCV particle is assembled is …

Short self-interacting N-terminal region of rubella virus capsid protein is essential for cooperative actions of capsid and nonstructural p150 proteins

M Sakata, N Otsuki, K Okamoto, M Anraku… - Journal of …, 2014 - Am Soc Microbiol
Nucleocapsid formation is a primary function of the rubella virus capsid protein, which also
promotes viral RNA synthesis via an unknown mechanism. The present study demonstrates …

Rubella virus capsid protein: a small protein with big functions

CS Ilkow, SD Willows, TC Hobman - Future microbiology, 2010 - Taylor & Francis
Virus replication occurs in the midst of a life or death struggle between the virus and the
infected host cell. To limit virus replication, host cells can activate a number of antiviral …

Mutations in the E1 hydrophobic domain of rubella virus impair virus infectivity but not virus assembly

Z Qiu, J Yao, H Cao, S Gillam - Journal of Virology, 2000 - Am Soc Microbiol
Rubella virus (RV) virions contain three structural proteins, a capsid protein that interacts
with viral genomic RNA to form a nucleocapsid and two membrane glycoproteins, E2 and …

Rubella virus-like replicon particles: analysis of encapsidation determinants and non-structural roles of capsid protein in early post-entry replication

C Claus, WP Tzeng, UG Liebert… - Journal of general …, 2012 - microbiologyresearch.org
Rubella virus (RUBV) contains a plus-strand RNA genome with two ORFs, one encoding the
non-structural replicase proteins (NS-ORF) and the second encoding the virion structural …

Factors affecting the non-structural functions of Rubella virus capsid

SD Willows - 2015 - era.library.ualberta.ca
During infection, the host cell environment must be altered to accommodate viral replication.
These alterations include hijacking cellular membranes as well as other components to form …