Microbiota-brain interactions: Moving toward mechanisms in model organisms

J Nagpal, JF Cryan - Neuron, 2021 - cell.com
Changes in the microbiota are associated with alterations in nervous system structure-
function and behavior and have been implicated in the etiology of neuropsychiatric and …

Chemosensory signal transduction in Caenorhabditis elegans

DM Ferkey, P Sengupta, ND L'Etoile - Genetics, 2021 - academic.oup.com
Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Assembly of the Caenorhabditis elegans gut microbiota from diverse soil microbial environments

M Berg, B Stenuit, J Ho, A Wang, C Parke… - The ISME …, 2016 - academic.oup.com
It is now well accepted that the gut microbiota contributes to our health. However, what
determines the microbiota composition is still unclear. Whereas it might be expected that the …

The functional repertoire contained within the native microbiota of the model nematode Caenorhabditis elegans

J Zimmermann, N Obeng, W Yang, B Pees… - The ISME …, 2020 - academic.oup.com
The microbiota is generally assumed to have a substantial influence on the biology of
multicellular organisms. The exact functional contributions of the microbes are often unclear …

Understanding the factors regulating host–microbiome interactions using Caenorhabditis elegans

A Singh, RJ Luallen - Philosophical Transactions of the …, 2024 - royalsocietypublishing.org
The Human Microbiome Project was a research programme that successfully identified
associations between microbial species and healthy or diseased individuals. However, a …

Biofilm matrix cloaks bacterial quorum sensing chemoattractants from predator detection

S Li, SY Liu, SY Chan, SL Chua - The ISME Journal, 2022 - academic.oup.com
Microbes often secrete high levels of quorum sensing (QS) autoinducers into the
environment to coordinate gene expression and biofilm formation, but risk detection and …

Identification of attractive odorants released by preferred bacterial food found in the natural habitats of C. elegans

SE Worthy, L Haynes, M Chambers, D Bethune, E Kan… - PloS one, 2018 - journals.plos.org
Food choice is critical for survival because organisms must choose food that is edible and
nutritious and avoid pathogenic food. Many organisms, including the nematode C. elegans …

Cilia structure and intraflagellar transport differentially regulate sensory response dynamics within and between C. elegans chemosensory neurons

A Philbrook, MP O'Donnell, L Grunenkovaite… - PLoS …, 2024 - journals.plos.org
Sensory neurons contain morphologically diverse primary cilia that are built by intraflagellar
transport (IFT) and house sensory signaling molecules. Since both ciliary structural and …

Indole‐associated predator–prey interactions between the nematode Caenorhabditis elegans and bacteria

JH Lee, YG Kim, M Kim, E Kim, H Choi… - Environmental …, 2017 - Wiley Online Library
Indole is an intercellular and interkingdom signalling molecule found in diverse ecological
niches. Caenorhabditis elegans is a bacterivorous nematode that lives in soil and compost …

C. elegans males integrate food signals and biological sex to modulate state-dependent chemosensation and behavioral prioritization

LR Wexler, RM Miller, DS Portman - Current Biology, 2020 - cell.com
Dynamic integration of internal and external cues is essential for flexible, adaptive behavior.
In C. elegans, biological sex and feeding state regulate expression of the food-associated …