Following the sequencing of the human genome and many other organisms, research on
protein-coding genes and their functions (functional genomics) has intensified …

Abstract● Introduction● Methods for proteomic analysis–Sample fractionation/biochemical
fractionation–MS● The cholesterol system–Cholesterol and apolipoproteins–Cholesterol …

Uromodulin is the most abundant protein in the urine. It is exclusively produced by renal
epithelial cells and it plays key roles in kidney function and disease. Uromodulin mainly …

The extracellular coat surrounding fish (vitelline envelope; VE) and mammalian (zona
pellucida; ZP) eggs is composed of long, interconnected filaments. Fish VE and mammalian …

Uromodulin is the most abundant protein secreted in urine, in which it is found as a high-
molecular-weight polymer. Polymerization occurs via its zona pellucida (ZP) domain, a …

Liver infection with hepatitis B virus (HBV), a DNA virus of the Hepadnaviridae family, leads
to severe disease, such as fibrosis, cirrhosis and hepatocellular carcinoma. The early steps …

The developing oocyte is surrounded by an acellular envelope that is composed of 2–4
isoforms of zona pellucida (ZP) proteins. The ZP proteins comprise the ZP1, ZP2, ZP3, and …

All fish eggs are surrounded by an envelope, called the zona pellucida (ZP), that plays
various roles during oogenesis, egg deposition, fertilization, and embryogenesis. The fish …

Tumor differentiation factor (TDF) is a recently discovered protein, produced by the pituitary
gland and secreted into the bloodstream. TDF and TDF-P1, a 20-amino acid peptide …

The combination of SDS‐PAGE and MS is one of the most powerful and perhaps most
frequently used gel‐based proteomics approaches in protein identification. However, one …