The manipulation of fluids in channels with dimensions of tens of micrometres—microfluidics—
has emerged as a distinct new field. Microfluidics has the potential to influence subject areas …

Microfabricated integrated circuits revolutionized computation by vastly reducing the space,
labor, and time required for calculations. Microfluidic systems hold similar promise for the …

▪ Abstract Since its inception just over a half century ago, the field of biomaterials has seen a
consistent growth with a steady introduction of new ideas and productive branches. This …

Substantial evidence shows that the heterogeneity of individual cells within a genetically
identical population can be critical to their chance of survival. Methods that use average …

Abstract Organ-on-a-chip (OOC, organ chip) technology can closely simulate the human
microenvironment, synthesize organ-like functional units on a fluidic chip substrate, and …

Various concentration gradient generation methods based on microfluidic systems are
summarized in this paper. The review covers typical structural characteristics, gradient …

Current models for protrusive motility in animal cells focus on cytoskeleton-based
mechanisms, where localized protrusion is driven by local regulation of actin biochemistry …

This review discusses the application of microfluidics in chemical biology. It aims to
introduce the reader to microfluidics, describe characteristics of microfluidic systems that are …

Microfluidic technology is creating powerful tools for cell biologists to control the complete
cellular microenvironment, leading to new questions and new discoveries. We review here …

Culturing cells at microscales allows control over microenvironmental cues, such as cell–cell
and cell–matrix interactions; the potential to scale experiments; the use of small culture …