Intestinal failure–associated liver disease: what do we know today?
DA Kelly - Gastroenterology, 2006 - Elsevier
Intestinal failure–associated liver disease develops in 40% to 60% of infants who require
long-term total parenteral nutrition (TPN) for intestinal failure and 15% to 40% of adults on …
long-term total parenteral nutrition (TPN) for intestinal failure and 15% to 40% of adults on …
Parenteral nutrition‐associated liver disease in adult and pediatric patients
VJ Kumpf - Nutrition in clinical practice, 2006 - Wiley Online Library
There are essentially 3 types of hepatobiliary disorders associated with parenteral nutrition
(PN) therapy: steatosis, cholestasis, and gallbladder sludge/stones. Reported prevalence …
(PN) therapy: steatosis, cholestasis, and gallbladder sludge/stones. Reported prevalence …
1. Guidelines on paediatric parenteral nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European …
B Koletzko, O Goulet, J Hunt, K Krohn… - Journal of pediatric …, 2005 - Wiley Online Library
BACKGROUND These Guidelines for Paediatric Parenteral Nutrition have been developed
as a mutual project of the European Society for Paediatric Gastroenterology, Hepatology …
as a mutual project of the European Society for Paediatric Gastroenterology, Hepatology …
LSD1‐demethylated LINC01134 confers oxaliplatin resistance through SP1‐induced p62 transcription in HCC
L Ma, A Xu, L Kang, R Cong, Z Fan, X Zhu, N Huo… - …, 2021 - Wiley Online Library
Background and Aims Oxaliplatin (OXA) is one of the most common chemotherapeutics in
advanced hepatocellular carcinoma (HCC), the resistance of which poses a big challenge …
advanced hepatocellular carcinoma (HCC), the resistance of which poses a big challenge …
Stigmasterol, a soy lipid–derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR
BA Carter, OA Taylor, DR Prendergast… - Pediatric …, 2007 - nature.com
Phytosterols, components of soy-derived lipids, are among the proposed exacerbants of
parenteral nutrition–associated cholestasis (PNAC). We investigated whether phytosterols …
parenteral nutrition–associated cholestasis (PNAC). We investigated whether phytosterols …
Overview of pediatric short bowel syndrome
D Duro, D Kamin, C Duggan - Journal of pediatric …, 2008 - Wiley Online Library
Short bowel syndrome (SBS) is a malabsorptive state occuring as a result of surgical
resection or congenital disease of a significant portion of the small intestine (1). The amount …
resection or congenital disease of a significant portion of the small intestine (1). The amount …
Mechanisms of disease: update on the molecular etiology and fundamentals of parenteral nutrition associated cholestasis
BA Carter, RJ Shulman - Nature clinical practice Gastroenterology & …, 2007 - nature.com
Since its introduction into clinical practice, parenteral nutrition has revolutionized the care of
premature neonates. Serum transaminase and bilirubin levels are commonly elevated in …
premature neonates. Serum transaminase and bilirubin levels are commonly elevated in …
Preventing parenteral nutrition liver disease
DA Kelly - Early human development, 2010 - Elsevier
Parenteral nutrition liver disease (PNLD) develops in 40–60% of infants who require long-
term PN for intestinal failure. The clinical spectrum includes hepatic steatosis, cholestasis …
term PN for intestinal failure. The clinical spectrum includes hepatic steatosis, cholestasis …
Neonatal cholestasis
E Lane, KF Murray - Pediatric Clinics, 2017 - pediatric.theclinics.com
Jaundice in the neonate is common, usually secondary to unconjugated or indirect
hyperbilirubinemia, and is most typically not dangerous to the infant. However, even in the …
hyperbilirubinemia, and is most typically not dangerous to the infant. However, even in the …
An overview of the current management of short-bowel syndrome in pediatric patients
M Muto, T Kaji, S Onishi, K Yano, W Yamada, S Ieiri - Surgery Today, 2022 - Springer
Short-bowel syndrome (SBS) is defined as a state of malabsorption after resection or loss of
a major portion of the bowel due to congenital or acquired factors. This article presents an …
a major portion of the bowel due to congenital or acquired factors. This article presents an …