Human breast tissue engineering in health and disease
MB Buchholz, DI Scheerman, R Levato… - EMBO Molecular …, 2024 - embopress.org
The human mammary gland represents a highly organized and dynamic tissue, uniquely
characterized by postnatal developmental cycles. During pregnancy and lactation, it …
characterized by postnatal developmental cycles. During pregnancy and lactation, it …
Novel Cancer Prevention Strategies in Individuals With Hereditary Cancer Syndromes: Focus on BRCA1, BRCA2, and Lynch Syndrome
Germline pathogenic variants (PVs) in the BRCA1 and BRCA2 genes confer elevated risks
of breast, ovarian, and other cancers. Lynch syndrome (LS) is associated with increased …
of breast, ovarian, and other cancers. Lynch syndrome (LS) is associated with increased …
[HTML][HTML] Obtention of viable cell suspensions from breast cancer tumor biopsies for 3D chromatin conformation and single-cell transcriptome analysis
A Stephenson-Gussinye… - Frontiers in Molecular …, 2024 - frontiersin.org
Molecular and cellular characterization of tumors is essential due to the complex and
heterogeneous nature of cancer. In recent decades, many bioinformatic tools and …
heterogeneous nature of cancer. In recent decades, many bioinformatic tools and …
Distinct granzyme k expression in immune cells: a single-cell rna-seq meta-analysis
HY Kim, H Ha - Genes & Genomics, 2024 - Springer
Background Granzymes are essential serine proteases in cytotoxic T cells and natural killer
(NK) cells, with GZMK's expression being less understood. This study aims to uncover GZMK …
(NK) cells, with GZMK's expression being less understood. This study aims to uncover GZMK …
Breast organoid suspension cultures maintain long-term estrogen receptor expression and responsiveness
J Brugge, KC Chang, F Silvestri, M Olipant… - 2024 - researchsquare.com
Organoid cultures offer a powerful technology to investigate many different aspects of
development, physiology, and pathology of diverse tissues. Unlike standard tissue culture of …
development, physiology, and pathology of diverse tissues. Unlike standard tissue culture of …