Eculizumab in atypical hemolytic uremic syndrome: strategies toward restrictive use
KL Wijnsma, C Duineveld, JFM Wetzels… - Pediatric …, 2019 - Springer
With the introduction of the complement C5-inhibitor eculizumab, a new era was entered for
patients with atypical hemolytic uremic syndrome (aHUS). Eculizumab therapy very …
patients with atypical hemolytic uremic syndrome (aHUS). Eculizumab therapy very …
Recurrent complement-mediated Hemolytic uremic syndrome after kidney transplantation
Hereditary forms of hemolytic uremic syndrome (HUS), formerly known as atypical HUS,
typically involve mutations in genes encoding for components of the alternative pathway of …
typically involve mutations in genes encoding for components of the alternative pathway of …
Long-term outcomes of the Atypical Hemolytic Uremic Syndrome after kidney transplantation treated with eculizumab as first choice
LGM De Andrade, MM Contti, HS Nga, AM Bravin… - PLoS …, 2017 - journals.plos.org
Introduction The treatment of choice for Atypical Hemolytic Uremic Syndrome (aHUS) is the
monoclonal antibody eculizumab. The objective of this study was to assess the efficacy and …
monoclonal antibody eculizumab. The objective of this study was to assess the efficacy and …
Midterm outcomes of 12 renal transplant recipients treated with eculizumab to prevent atypical hemolytic syndrome recurrence
C Levi, V Frémeaux-Bacchi, J Zuber, M Rabant… - …, 2017 - journals.lww.com
Background Atypical hemolytic uremic syndrome (aHUS) is an orphan disease with a high
rate of recurrence after kidney transplantation. However, reports of successful prevention of …
rate of recurrence after kidney transplantation. However, reports of successful prevention of …
[HTML][HTML] A case report and literature review of eculizumab withdrawal in atypical hemolytic-uremic syndrome
B Quiroga, A de Lorenzo, C Vega… - The American Journal of …, 2016 - ncbi.nlm.nih.gov
Objective: Unusual clinical course Background: Recent advances in the treatment of atypical
hemolytic-uremic syndrome (aHUS) have resulted to better long-term survival rates for …
hemolytic-uremic syndrome (aHUS) have resulted to better long-term survival rates for …
Pediatric Renal Transplantation
A Chen, JJ Lin, AM South - Kidney Transplantation, Bioengineering and …, 2017 - Elsevier
Kidney transplantation is the treatment of choice for pediatric patients with end-stage renal
disease. With the advance in immunosuppression, surgical techniques, and posttransplant …
disease. With the advance in immunosuppression, surgical techniques, and posttransplant …