[HTML][HTML] Adipose tissue inflammation and pulmonary dysfunction in obesity

G Palma, GP Sorice, VA Genchi, F Giordano… - International Journal of …, 2022 - mdpi.com
Obesity is a chronic disease caused by an excess of adipose tissue that may impair health
by altering the functionality of various organs, including the lungs. Excessive deposition of …

[HTML][HTML] Sleep, testosterone and cortisol balance, and ageing men

PY Liu, RT Reddy - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Sleep serves important biological functions, and influences health and longevity through
endocrine and metabolic related systems. Sleep debt, circadian misalignment and sleep …

Critical evaluation of different available guidelines for late‐onset hypogonadism

VA Giagulli, M Castellana, G Lisco, V Triggiani - Andrology, 2020 - Wiley Online Library
Background Late‐onset hypogonadism (LOH) is a syndrome characterized by clinical and
biochemical evidence of low testosterone levels with advancing age. In recent years, several …

Approach to the patient: the evaluation and management of men≥ 50 years with low Serum testosterone concentration

M Grossmann, CN Jayasena… - The Journal of Clinical …, 2023 - academic.oup.com
Although testosterone replacement in men with classic hypogonadism due to an identified
pathology of the hypothalamic-pituitary-testicular axis is uncontroversial, the role of …

Sperm DNA damage: the possible link between obesity and male infertility, an update of the current literature

A Peel, A Saini, JC Deluao, NO McPherson - Andrology, 2023 - Wiley Online Library
Obesity prevalence worldwide is increasing significantly. Whilst maternal obesity has clear
detrimental impacts on fertility, pregnancy and foetal outcomes, more recently there has …

Association between obstructive sleep apnea and male serum testosterone: A systematic review and meta‐analysis

L Su, YH Meng, SZ Zhang, Y Cao, J Zhu, H Qu… - …, 2022 - Wiley Online Library
Background Currently, there is no consensus on the effect of obstructive sleep apnea on
male serum testosterone levels. This systematic review and meta‐analysis aimed to …

[HTML][HTML] Sleep apnea syndrome associated with gonadal hormone imbalance

C Cojocaru, E Cojocaru… - Biomedical …, 2023 - spandidos-publications.com
Patients with obstructive sleep apnea exhibit an increased risk of developing gonadal
disorders. Because a notable number of people worldwide have sleep respiratory and …

Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring

AI Campos, N Ingold, Y Huang, BL Mitchell, PF Kho… - Sleep, 2023 - academic.oup.com
Abstract Study Objectives Despite its association with severe health conditions, the etiology
of sleep apnea (SA) remains understudied. This study sought to identify genetic variants …

Controversies in testosterone therapy

DK Twitchell, AW Pastuszak… - Sexual Medicine …, 2021 - academic.oup.com
Introduction Testosterone prescriptions have increased dramatically in recent years, largely
because of changes in expert guidelines. Concerns have been raised that testosterone …

Obstructive sleep apnea is associated with polycythemia in hypogonadal men on testosterone replacement therapy

SD Lundy, NV Parekh… - The journal of sexual …, 2020 - academic.oup.com
Background Polycythemia (erythrocytosis) is a known side effect of testosterone (T)
replacement therapy (TRT) and appears to correlate with maximum T levels. There is also a …