Clinical consequences of polypharmacy in elderly

RL Maher, J Hanlon, ER Hajjar - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

What do we know about frailty in the acute care setting? A scoping review

O Theou, E Squires, K Mallery, JS Lee, S Fay… - BMC geriatrics, 2018 - Springer
Background The ability of acute care providers to cope with the influx of frail older patients is
increasingly stressed, and changes need to be made to improve care provided to older …

Polypharmacy in elderly patients

ER Hajjar, AC Cafiero, JT Hanlon - The American journal of geriatric …, 2007 - Elsevier
Background: Polypharmacy (ie, the use of multiple medications and/or the administration of
more medications than are clinically indicated, representing unnecessary drug use) is …

Prevention of potentially inappropriate prescribing for elderly patients: a randomized controlled trial using STOPP/START criteria

PF Gallagher, MN O'connor… - Clinical Pharmacology & …, 2011 - Wiley Online Library
Inappropriate prescribing is particularly common in older patients and is associated with
adverse drug events (ADEs), hospitalization, and wasteful utilization of resources. We …

Polypharmacy, adverse drug reactions, and geriatric syndromes

BM Shah, ER Hajjar - Clinics in geriatric medicine, 2012 - geriatric.theclinics.com
The older population, composed of adults aged 65 years or older, is the fastest growing
segment of the United States population. The Administration of Aging of the United States …

Appropriate prescribing in elderly people: how well can it be measured and optimised?

A Spinewine, KE Schmader, N Barber, C Hughes… - The Lancet, 2007 - thelancet.com
Prescription of medicines is a fundamental component of the care of elderly people, and
optimisation of drug prescribing for this group of patients has become an important public …

Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three‐year period in an elderly population

J Jyrkkä, H Enlund, P Lavikainen… - … and drug safety, 2011 - Wiley Online Library
Purpose To determine the association of polypharmacy with nutritional status, functional
ability and cognitive capacity among elderly persons. Methods This was a prospective …

Inappropriate prescribing: criteria, detection and prevention

MN O'Connor, P Gallagher, D O'Mahony - Drugs & aging, 2012 - Springer
Inappropriate prescribing is highly prevalent in older people and is a major healthcare
concern because of its association with negative healthcare outcomes including adverse …

The medication appropriateness index at 20: where it started, where it has been, and where it may be going

JT Hanlon, KE Schmader - Drugs & aging, 2013 - Springer
Potentially inappropriate prescribing for older adults is a major public health concern. While
there are multiple measures of potentially inappropriate prescribing, the medication …

Polypharmacy status as an indicator of mortality in an elderly population

J Jyrkkä, H Enlund, MJ Korhonen, R Sulkava… - Drugs & aging, 2009 - Springer
Background Increased use of drugs has raised concern about the risks of polypharmacy in
elderly populations. Adverse outcomes, such as hospitalizations and falls, have been shown …