The emergence, genomic diversity and global spread of SARS-CoV-2
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …
Testing at scale during the COVID-19 pandemic
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …
CoV-2) genome in January 2020 enabled the immediate development of tests to detect the …
[HTML][HTML] Spike mutation D614G alters SARS-CoV-2 fitness
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein
substitution D614G became dominant during the coronavirus disease 2019 (COVID-19) …
substitution D614G became dominant during the coronavirus disease 2019 (COVID-19) …
[HTML][HTML] Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence
S Rahman, MTV Montero, K Rowe… - Expert review of …, 2021 - Taylor & Francis
Introduction The COVID-19 pandemic has created a public health crisis, infected millions of
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …
Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic
Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …
The SARS-CoV-2 spike glycoprotein biosynthesis, structure, function, and antigenicity: implications for the design of spike-based vaccine immunogens
L Duan, Q Zheng, H Zhang, Y Niu, Y Lou… - Frontiers in …, 2020 - frontiersin.org
The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …
respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a grave threat to global public …
[HTML][HTML] Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus
A SARS-CoV-2 variant carrying the Spike protein amino acid change D614G has become
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …
the most prevalent form in the global pandemic. Dynamic tracking of variant frequencies …
Ultrafast Sample placement on Existing tRees (UShER) enables real-time phylogenetics for the SARS-CoV-2 pandemic
As the SARS-CoV-2 virus spreads through human populations, the unprecedented
accumulation of viral genome sequences is ushering in a new era of 'genomic contact …
accumulation of viral genome sequences is ushering in a new era of 'genomic contact …
Temporal detection and phylogenetic assessment of SARS-CoV-2 in municipal wastewater
SARS-CoV-2 has recently been detected in feces, which indicates that wastewater may be
used to monitor viral prevalence in the community. Here, we use RT-qPCR to monitor …
used to monitor viral prevalence in the community. Here, we use RT-qPCR to monitor …