The ecology and evolution of pangenomes
Since the first genome-scale comparisons, it has been evident that the genomes of many
species are unbound by strict vertical descent: Large differences in gene content can occur …
species are unbound by strict vertical descent: Large differences in gene content can occur …
The role of integrative and conjugative elements in antibiotic resistance evolution
J Botelho, H Schulenburg - Trends in microbiology, 2021 - cell.com
Mobile genetic elements (MGEs), such as plasmids and integrative and conjugative
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …
Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes
It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
Non-antibiotic pharmaceuticals promote the transmission of multidrug resistance plasmids through intra-and intergenera conjugation
Antibiotic resistance is a global threat to public health. The use of antibiotics at sub-inhibitory
concentrations has been recognized as an important factor in disseminating antibiotic …
concentrations has been recognized as an important factor in disseminating antibiotic …
RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistance
AL Colclough, I Alav, EE Whittle, HL Pugh… - Future …, 2020 - Taylor & Francis
Rresistance-nodulation-division (RND) efflux pumps in Gram-negative bacteria remove
multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore …
multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore …
Host-specific plasmid evolution explains the variable spread of clinical antibiotic-resistance plasmids
F Benz, AR Hall - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Antibiotic resistance encoded on plasmids is a pressing global health problem. Predicting
which plasmids spread in the long term remains very challenging, even though some key …
which plasmids spread in the long term remains very challenging, even though some key …
Plasmids persist in a microbial community by providing fitness benefit to multiple phylotypes
The current epidemic of antibiotic resistance has been facilitated by the wide and rapid
horizontal dissemination of antibiotic resistance genes (ARGs) in microbial communities …
horizontal dissemination of antibiotic resistance genes (ARGs) in microbial communities …
Colonization of gut microbiota by plasmid-carrying bacteria is facilitated by evolutionary adaptation to antibiotic treatment
Multidrug-resistant plasmid-carrying bacteria are of particular clinical concern as they could
transfer antibiotic resistance genes to other bacterial species. However, little is known …
transfer antibiotic resistance genes to other bacterial species. However, little is known …
Removal behavior and key drivers of antibiotic resistance genes in two full-scale leachate treatment plants
Leachate is a critical reservoir of antibiotic resistance genes (ARGs) and its proper treatment
is closely related to human health and ecosystem safety. Here, we used high-throughput …
is closely related to human health and ecosystem safety. Here, we used high-throughput …
Antibiotic resistome associated with microbial communities in an integrated wastewater reclamation system
K Yu, P Li, Y Chen, B Zhang, Y Huang, FY Huang, Y He - Water research, 2020 - Elsevier
Antibiotic resistome is a raising concern around the world, especially considering treated
wastewater for reclamation. A wastewater reclamation system (WWRS), composed by a …
wastewater for reclamation. A wastewater reclamation system (WWRS), composed by a …