Nitric oxide signaling in health and disease

JO Lundberg, E Weitzberg - Cell, 2022 - cell.com
The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …

Detection, identification, and quantification of oxidative protein modifications

CL Hawkins, MJ Davies - Journal of Biological Chemistry, 2019 - ASBMB
Exposure of biological molecules to oxidants is inevitable and therefore commonplace.
Oxidative stress in cells arises from both external agents and endogenous processes that …

A forty year journey: The generation and roles of NO in plants

ZS Kolbert, JB Barroso, R Brouquisse, FJ Corpas… - Nitric Oxide, 2019 - Elsevier
In this year there is the 40th anniversary of the first publication of plant nitric oxide (NO)
emission by Lowell Klepper. In the decades since then numerous milestone discoveries …

Nitric oxide regulation of plant metabolism

KJ Gupta, VC Kaladhar, TB Fitzpatrick, AR Fernie… - Molecular Plant, 2022 - cell.com
Nitric oxide (NO) has emerged as an important signal molecule in plants, having myriad
roles in plant development. In addition, NO also orchestrates both biotic and abiotic stress …

Nitric oxide function in plant abiotic stress

NN Fancy, AK Bahlmann, GJ Loake - Plant, cell & environment, 2017 - Wiley Online Library
Abiotic stress is one of the main threats affecting crop growth and production. An
understanding of the molecular mechanisms that underpin plant responses against …

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

CE Paulsen, KS Carroll - Chemical reviews, 2013 - ACS Publications
Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS,
respectively, are produced during normal cell function and in response to various stimuli. An …

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Redox signaling mediated by thioredoxin and glutathione systems in the central nervous system

X Ren, L Zou, X Zhang, V Branco, J Wang… - Antioxidants & redox …, 2017 - liebertpub.com
Abstract Significance: The thioredoxin (Trx) and glutathione (GSH) systems play important
roles in maintaining the redox balance in the brain, a tissue that is prone to oxidative stress …

Thioredoxins, glutaredoxins, and peroxiredoxins—molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling

EM Hanschmann, JR Godoy, C Berndt… - Antioxidants & redox …, 2013 - liebertpub.com
Abstract Thioredoxins (Trxs), glutaredoxins (Grxs), and peroxiredoxins (Prxs) have been
characterized as electron donors, guards of the intracellular redox state, and “antioxidants” …

Implications of glial nitric oxide in neurodegenerative diseases

JE Yuste, E Tarragon, CM Campuzano… - Frontiers in cellular …, 2015 - frontiersin.org
Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …