The phenomenon of agonist-antagonist muscle coactivation is discussed with respect to its
consequences for movement mechanics (such as increasing joint apparent stiffness …

Biological sex is a primary determinant of athletic performance because of fundamental sex
differences in anatomy and physiology dictated by sex chromosomes and sex hormones …

Key points The mechanisms responsible for the loss in muscle power and increased
fatigability with ageing are unresolved. We show that the contractile mechanics of fibres from …

Muscle strength, the maximal force-generating capacity of a muscle or group of muscles, is
regularly assessed in physiological experiments and clinical trials. An understanding of the …

Whether there are age-related differences in neural drive during maximal effort contractions
is not clear. This review determined the effect of age on voluntary activation during maximal …

Physical performance fatigue can be ascribed to both peripheral and central components.
Central fatigue, however, is an elusive entity, consisting of cognitive/sensory component and …

Adult aging is associated with a myriad of changes within the neuromuscular system,
leading to reductions in contractile function of old adults. One of the consequences of these …

It is poorly understood how healthy aging affects neural mechanisms underlying motor
learning. We used blood-oxygen-level dependent (BOLD) contrasts to examine age-related …

Even in the absence of disease or disability, aging is associated with marked physiological
adaptations within the neuromuscular system. An ability to perform activities of daily living …

Aim Decreased muscle strength has been frequently observed in individuals with
Parkinson's disease (PD). However, this condition is still poorly examined in physically …