[HTML][HTML] Icariin treatment rescues diabetes induced bone loss via scavenging ROS and activating primary cilia/Gli2/osteocalcin signaling pathway

J Liu, Q Cheng, X Wu, H Zhu, X Deng, M Wang, S Yang… - Cells, 2022 - mdpi.com
Diabetes-associated bone complications lead to fragile bone mechanical strength and
osteoporosis, aggravating the disease burden of patients. Advanced evidence shows that …

[HTML][HTML] Alterations of the gut microbiota and metabolites by ShenZhu TiaoPi granule alleviates hyperglycemia in GK rats

J Zhao, Z Fang - Frontiers in Microbiology, 2024 - frontiersin.org
ShenZhu TiaoPi granule (STG) is a compound prescription that is used in Chinese medicine
for the treatment of type 2 diabetes mellitus (T2DM). Previous studies have indicated a …

[HTML][HTML] Metabolomic profiling reveals the step-wise alteration of bile acid metabolism in patients with diabetic kidney disease

Q Zhang, L Lu, J Wang, M Lu, D Liu, C Zhou… - Nutrition & Diabetes, 2024 - nature.com
Background Diabetic kidney disease (DKD) is the major complication of diabetes
concomitant with gut dysbiosis and glycometabolic disorder, which are strongly associated …

[HTML][HTML] Oxidative Stress and Histomorphometric Remodeling: Two Key Intestinal Features of Type 2 Diabetes in Goto–Kakizaki Rats

M Esteves-Monteiro, M Ferreira-Duarte… - International Journal of …, 2024 - mdpi.com
Gastrointestinal complications of diabetes are often overlooked, despite affecting up to 75%
of patients. This study innovatively explores local glutathione levels and morphometric …

[HTML][HTML] Effect of Tangshen formula on the remodeling of small intestine and colon in Zucker diabetic fatty rats

X Yang, J Zhao, H Li, L Pan, J Guo, J Li, Y Zhang… - Heliyon, 2023 - cell.com
Background and aim Previous study have demonstrated that Tangshen Formula (TSF) could
attenuate colonic histomorphological remodeling in the diabetic rat model induced by high …

[HTML][HTML] In vitro models of tissue and organ regeneration

PC Baer, R Schubert - International journal of molecular sciences, 2023 - mdpi.com
The recovery of cells after tissue and organ injury is a complex process. To understand the
underlying molecular biological mechanisms, more detailed insights into the cellular …

[PDF][PDF] Prevention of colon enlargement by TNF-α antagonist in a streptozotocin-induced diabetic rat model

Summary. Purpose. We investigated the effect of tumor necrosis factor (TNF)-α antagonist on
the structure and function of the streptozotocin-nicotinamide (STZ-NA)-induced diabetic rat …

Metabolomic profiling reveals the step-wise alteration of bile acid metabolism in patients with diabetic kidney disease

Z Liu, Q Zhang, L Lu, J Wang, M Lu, D Liu, C Zhou - 2024 - researchsquare.com
Background Diabetic kidney disease (DKD) is the major complication of diabetes
concomitant with gut dysbiosis and glycometabolic disorder, which are strongly associated …

[HTML][HTML] Lactococcus lactis expressando HSP65 protege contra o desenvolvimento de diabetes tipo 1 por meio da indução de células dendríticas tolerogênicas via …

JE Oliveira - 2024 - bdtd.ibict.br
O Diabetes mellitus tipo 1 é caracterizado pela destruição de células beta produtoras de
insulina, resultando em hiperglicemia. Novas estratégias terapêuticas são importantes para …

Small intestine histologic neuronal features of type-2 diabetes mellitus rats treated with ethanolic extract red betel leaf (Piper crocatum) nanoparticle (EERbLNp)

TW Pangestiningsih, RA Primatika… - Livestock and Animal …, 2023 - jurnal.uns.ac.id
Objective: This study marked histological features of small intestine neurons in the type-2
diabetes mellitus (T2DM) rat model treated with ethanolic extract red betel leaf nanoparticle …