Intraoperative imaging in pathology-assisted surgery

FJ Voskuil, J Vonk, B van der Vegt, S Kruijff… - Nature biomedical …, 2022 - nature.com
The pathological assessment of surgical specimens during surgery can reduce the
incidence of positive resection margins, which otherwise can result in additional surgeries or …

Review of intraoperative optical coherence tomography: technology and applications

OM Carrasco-Zevallos, C Viehland, B Keller… - Biomedical optics …, 2017 - opg.optica.org
During microsurgery, en face imaging of the surgical field through the operating microscope
limits the surgeon's depth perception and visualization of instruments and sub-surface …

Surgical margins in oral cavity squamous cell carcinoma: current practices and future directions

JJ Kain, AC Birkeland, N Udayakumar… - The …, 2020 - Wiley Online Library
Objective To discuss the current available techniques for intraoperative margin assessment
in the surgical treatment of oral squamous cell carcinoma (OSCC) through a review of the …

[HTML][HTML] Machine-learning assisted discrimination of precancerous and cancerous from healthy oral tissue based on multispectral autofluorescence lifetime imaging …

E Duran-Sierra, S Cheng, R Cuenca, B Ahmed, J Ji… - Cancers, 2021 - mdpi.com
Simple Summary Complete resection of dysplastic and malignant tissue improves overall
survival and delays cancer recurrence in oral cancer patients; however, intraoperative …

Surgical margins in head and neck cancer: Intra-and postoperative considerations

KT Robbins, A Triantafyllou, C Suárez, F López… - Auris Nasus …, 2019 - Elsevier
Objective To provide a perspective on the significance of recent reports for optimizing cancer
free surgical margins that have challenged standard practices. Methods We conducted a …

[HTML][HTML] Cancer surgery 2.0: guidance by real-time molecular technologies

N Ogrinc, P Saudemont, Z Takats, M Salzet… - Trends in Molecular …, 2021 - cell.com
In vivo cancer margin delineation during surgery remains a major challenge. Despite the
availability of several image guidance techniques and intraoperative assessment, clear …

Water concentration analysis by Raman spectroscopy to determine the location of the tumor border in oral cancer surgery

EM Barroso, RWH Smits, CGF van Lanschot… - Cancer research, 2016 - AACR
Adequate resection of oral cavity squamous cell carcinoma (OCSCC) means complete
tumor removal with a clear margin of more than 5 mm. For OCSCC, 85% of the surgical …

[HTML][HTML] The clinical usefulness of optical coherence tomography during cancer interventions

L van Manen, J Dijkstra, C Boccara, E Benoit… - Journal of cancer …, 2018 - Springer
Introduction Tumor detection and visualization plays a key role in the clinical workflow of a
patient with suspected cancer, both in the diagnosis and treatment. Several optical imaging …

Advancements in Intraoperative Near-Infrared Fluorescence Imaging for Accurate Tumor Resection: A Promising Technique for Improved Surgical Outcomes and …

SK Rainu, RG Ramachandran… - ACS Biomaterials …, 2023 - ACS Publications
Clear surgical margins for solid tumor resection are essential for preventing cancer
recurrence and improving overall patient survival. Complete resection of tumors is often …

[HTML][HTML] An overview of the current clinical status of optical imaging in head and neck cancer with a focus on Narrow Band imaging and fluorescence optical imaging

JE van Schaik, GB Halmos, MJH Witjes, BEC Plaat - Oral Oncology, 2021 - Elsevier
Early and accurate identification of head and neck squamous cell carcinoma (HNSCC) is
important to improve treatment outcomes and prognosis. New optical imaging techniques …