Small molecule, dietary antioxidants exert a remarkably broad range of bioactivities, and
many of these can be explained by the influence of antioxidants on the redox homeostasis …

Lignans and neolignans are plant secondary metabolites derived from the oxidative
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …

Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

Flaxseed consumption (Linum usitatissimum L.) has increased due to its potential health
benefits, such as protection against inflammation, diabetes, cancer, and cardiovascular …

Secoisolariciresinol diglucoside (SDG), found mainly in flaxseed, is one of the essential
lignans. SDG, as well as the beneficial fatty acid composition and high fiber content, has …

Cell migration and invasion play an important role in the development of cancer. Cell
migration is associated with several specific actin filament–based structures, including …

Flaxseeds have been known for their anti-cancerous effects due to the high abundance of
lignans released upon ingestion. The most abundant lignan, secoisolariciresinol diglucoside …

RESULTS Administration with up to 40 µM luteolin showed no cytotoxic activity on lung
cancer A549 cells or non-cancer MRC-5 cells. Additionally, luteolin at 20–40 µM significantly …

Currently cancer is the second leading cause of death globally and worldwide incidence
and mortality rates of all cancers of males and females are rising tremendously. In spite of …

Lignans are known dietary polyphenols found in cereals, plants and seeds. Flaxseed is one
of the major sources of lignans mainly existing in the form of secoisolariciresinol diglucoside …