Advances in pyranopyrazole scaffolds' syntheses using sustainable catalysts—a review

RK Ganta, N Kerru, S Maddila, SB Jonnalagadda - Molecules, 2021 - mdpi.com
Heterogeneous catalysis plays a crucial role in many chemical processes, including
advanced organic preparations and the design and synthesis of new organic moieties …

[PDF][PDF] Synthesis, characterization and evaluation of some Pyranopyrazole derivatives as multifunction additives for medium lubricating Oils

AR Salih, ZAK Al-Messri - Iraqi Journal of Science, 2022 - iasj.net
The current work involves synthesis of 6-amino-4-(4-hydroxyl-3-methoxyphenyl)-3-methyl-1-
phenyl-1, 4- dihydropyrano [2, 3-c] pyrazole-5-carbonitrile (2) by condensation of 2-(4 …

Visible-light induced acridinium catalysed synthesis of biologically active dihydropyranopyrazoles scaffolds via HAT

M Mishra, PP Singh, P Nainwal, S Tivari, V Srivastava - Tetrahedron Letters, 2023 - Elsevier
Visible light driven acridinium catalysed synthesis of dihydropyranopyrazole scaffolds from
pyrazol and butyne derivatives under an air atmosphere is reported at room temperature …

Molecular modelling, synthesis and antimicrobial evaluation of benzimidazole nucleoside mimetics

H Chaurasia, VK Singh, R Mishra, AK Yadav… - Bioorganic …, 2021 - Elsevier
A series of new N-1-(β-d-ribofuranosyl) benzimidazole derivatives has been designed using
in silico methods and synthesized as probable antimicrobial agents. Further, the compounds …

Targeting disease with benzoxazoles: a comprehensive review of recent developments

A Abdullahi, KY Yeong - Medicinal Chemistry Research, 2024 - Springer
Benzoxazole is an attractive scaffold in medicinal chemistry due to its diverse biological
applications. From 2016 to 2023, a plethora of benzoxazole derivatives have been …

2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases

A Fuentes-Aguilar, P Merino-Montiel… - Journal of Enzyme …, 2022 - Taylor & Francis
We have carried out the design, synthesis, and evaluation of a small library of 2-
aminobenzoxazole-appended coumarins as novel inhibitors of tumour-related CAs IX and …

Design, docking, molecular dynamics, synthesis and antimicrobial studies on quinoline derivatives and some isosteres

VK Singh, I Ahmad, H Patel, J Dwivedi, P Singh… - Journal of Molecular …, 2023 - Elsevier
The computer added design, synthesis, antibacterial and antifungal activities of a series of
quinoline derivatives and some isosteres are reported. In silico studies using autodock …

Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic …

M Almaghrabi, A Musa, AKB Aljohani… - Journal of …, 2024 - Taylor & Francis
Microbiological DNA gyrase is recognized as an exceptional microbial target for the
innovative development of low-resistant and more effective antimicrobial drugs. Hence, we …

Molecular docking and antibacterial studies of pyranopyrazole derivatives synthesized using [Pap-Glu@ Chi] biocatalyst through a greener approach

A Agrwal, RK Pathak, V Kasana - Arabian Journal for Science and …, 2022 - Springer
In the present work, papain enzyme was immobilized on a polymer support chitosan through
a linkage of glutaraldehyde to form the [Pap-Glu@ Chi] biocatalyst through the covalent …

Synthesis and characterization of derivatives including thiazolidine-2,4-dione/1-H- imidazole and evaluation of antimicrobial, antioxidant, and cytotoxic properties of …

HY Nyaki, NO Mahmoodi - Research on Chemical Intermediates, 2021 - Springer
Several new derivatives of thiazolidine-2, 4-dione and 1-H-imidazole were prepared using
imidazole aldehydes 6a–6f in ethanol as a solvent. Products 7a–7f were obtained in …