DNA structure and function

A Travers, G Muskhelishvili - The FEBS journal, 2015 - Wiley Online Library
The proposal of a double‐helical structure for DNA over 60 years ago provided an eminently
satisfying explanation for the heritability of genetic information. But why is DNA, and not …

Condensed DNA: condensing the concepts

VB Teif, K Bohinc - Progress in biophysics and molecular biology, 2011 - Elsevier
DNA is stored in vivo in a highly compact, so-called condensed phase, where gene
regulatory processes are governed by the intricate interplay between different states of DNA …

Electrostatic interactions in biological DNA-related systems

AG Cherstvy - Physical Chemistry Chemical Physics, 2011 - pubs.rsc.org
In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Carbon nanopores for DNA sequencing: a review on nanopore materials

J Xu, X Jiang, N Yang - Chemical Communications, 2023 - pubs.rsc.org
In the past decades nanometer-scale pores have been employed as a powerful tool for
sensing biological molecules. In pursuit of such a technology, a variety of nanotechnology …

Sequence-dependent DNA condensation as a driving force of DNA phase separation

H Kang, J Yoo, BK Sohn, SW Lee, HS Lee… - Nucleic acids …, 2018 - academic.oup.com
The physical properties of DNA have been suggested to play a central role in spatio-
temporal organization of eukaryotic chromosomes. Experimental correlations have been …

New aspects of magnesium function: a key regulator in nucleosome self-assembly, chromatin folding and phase separation

T Ohyama - International journal of molecular sciences, 2019 - mdpi.com
Metal cations are associated with many biological processes. The effects of these cations on
nucleic acids and chromatin were extensively studied in the early stages of nucleic acid and …

Direct recognition of homology between double helices of DNA in Neurospora crassa

E Gladyshev, N Kleckner - Nature communications, 2014 - nature.com
Chromosomal regions of identical or nearly identical DNA sequence can preferentially
associate with one another in the apparent absence of DNA breakage. Molecular …

Electric and electrophoretic inversion of the DNA charge in multivalent electrolytes

B Luan, A Aksimentiev - Soft Matter, 2010 - pubs.rsc.org
Counterion-induced inversion of the DNA charge was characterized through extensive
molecular dynamics simulations. We observed reversal of the DNA motion in an external …

Bullied no more: when and how DNA shoves proteins around

JM Fogg, GL Randall, BM Pettitt, LS De Witt… - Quarterly reviews of …, 2012 - cambridge.org
The predominant protein-centric perspective in protein–DNA-binding studies assumes that
the protein drives the interaction. Research focuses on protein structural motifs, electrostatic …

Nontrivial quantum and quantum-like effects in biosystems: Unsolved questions and paradoxes

AV Melkikh, A Khrennikov - Progress in Biophysics and Molecular Biology, 2015 - Elsevier
Non-trivial quantum effects in biological systems are analyzed. Some unresolved issues and
paradoxes related to quantum effects (Levinthal's paradox, the paradox of speed, and …