Despite decades of bile acid research, diverse biological roles for bile acids have been
discovered recently due to developments in understanding the human microbiota. As …

The diversity, composition, and function of the bacterial community inhabiting the human
gastrointestinal tract contributes to host health through its role in producing energy or …

A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …

Gut microbiota has evolved along with their hosts and is an integral part of the human body.
Microbiota acquired at birth develops in parallel as the host develops and maintains its …

Bile acid biotransformation is a collaborative effort by the host and the gut microbiome. Host
hepatocytes synthesize primary bile acids from cholesterol. Once these host-derived primary …

Cirrhosis–the common end-stage of chronic liver disease–is associated with a cascade of
events, of which intestinal bacterial overgrowth and dysbiosis are central. Bacterial toxins …

The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor …

Fecal microbiota transplantation (FMT) is a method to directly change the recipient's gut
microbiota to normalize the composition and gain a therapeutic benefit. The history of FMT …

The female reproductive tract (FRT), similar to other mucosal sites, harbours a site-specific
microbiome, which has an essential role in maintaining health and homeostasis. In the …

Developments in high-throughput microbial genomic sequencing and other systems biology
techniques have given novel insight into the potential contribution of the gut microbiota to …