Hyperpolarized (HP) carbon 13 (13C) MRI is an emerging molecular imaging method that
allows rapid, noninvasive, and pathway-specific investigation of dynamic metabolic and …

Rationale: The recent development of hyperpolarized 13C magnetic resonance
spectroscopy has made it possible to measure cellular metabolism in vivo, in real time …

Hyperpolarization is an emerging method in magnetic resonance imaging that allows
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …

This study aimed to investigate real-time early detection of metabolic alteration in a rat
model with acute myocardial ischemia-reperfusion (AMI/R) injury and myocardial necrosis …

Background Prolonged ischemia and myocardial infarction are followed by a series of
dynamic processes that determine the fate of the affected myocardium toward recovery or …

Purpose The purpose of this work was to study the contribution of liver [1‐13C] lactate to the
lactate signal detected in the heart following injection of hyperpolarized [1‐13C] pyruvate …

Although non-invasive perfusion and viability imaging often provide the gateway to coronary
revascularisation, current non-invasive imaging methods only report the surrogate markers …

Dissolution DNP has become an important method to generate highly polarized substrates
such as pyruvic acid for in vivo imaging and localized spectroscopy. In a quest to further …

Hyperpolarized 13C Magnetic Resonance Imaging Can Detect Metabolic Changes
Characteristic of Penumbra in Ischemic Stroke Page 1 Hyperpolarized 13C Magnetic …

Cardiovascular disease is the leading cause of death world-wide. It is increasingly
recognised that cardiac pathologies show, or may even be caused by, changes in …