Efficacy of deep brain stimulation for treatment-resistant obsessive-compulsive disorder: systematic review and meta-analysis

R Gadot, R Najera, S Hirani, A Anand… - Journal of Neurology …, 2022 - jnnp.bmj.com
Deep brain stimulation (DBS) is an established and growing intervention for treatment-
resistant obsessive-compulsive disorder (TROCD). We assessed current evidence on the …

[HTML][HTML] Deep brain stimulation beyond the clinic: Navigating the future of Parkinson's and Alzheimer's disease therapy

DKL Senevirathne, A Mahboob, K Zhai, P Paul… - Cells, 2023 - mdpi.com
Deep brain stimulation (DBS) is a surgical procedure that uses electrical neuromodulation to
target specific regions of the brain, showing potential in the treatment of neurodegenerative …

[HTML][HTML] A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder

N Li, JC Baldermann, A Kibleur, S Treu… - Nature …, 2020 - nature.com
Multiple surgical targets for treating obsessive-compulsive disorder with deep brain
stimulation (DBS) have been proposed. However, different targets may modulate the same …

Probabilistic mapping of deep brain stimulation: insights from 15 years of therapy

GJB Elias, A Boutet, SE Joel, J Germann… - Annals of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) depends on precise delivery of electrical current to target
tissues. However, the specific brain structures responsible for best outcome are still debated …

A unified functional network target for deep brain stimulation in obsessive-compulsive disorder

N Li, B Hollunder, JC Baldermann, A Kibleur, S Treu… - Biological …, 2021 - Elsevier
Background Multiple deep brain stimulation (DBS) targets have been proposed for treating
intractable obsessive-compulsive disorder (OCD). Here, we investigated whether stimulation …

[HTML][HTML] Therapeutic neurostimulation in obsessive-compulsive and related disorders: A systematic review

N Acevedo, P Bosanac, T Pikoos, S Rossell, D Castle - Brain sciences, 2021 - mdpi.com
Invasive and noninvasive neurostimulation therapies for obsessive-compulsive and related
disorders (OCRD) were systematically reviewed with the aim of assessing clinical …

[HTML][HTML] Deep brain stimulation for obsessive-compulsive disorder: A systematic review of worldwide experience after 20 years

L Mar-Barrutia, E Real, C Segalás… - World journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Twenty years after its first use in a patient with obsessive-compulsive
disorder (OCD), the results confirm that deep brain stimulation (DBS) is a promising therapy …

Deep brain stimulation of the “medial forebrain bundle”: a strategy to modulate the reward system and manage treatment-resistant depression

AJ Fenoy, J Quevedo, JC Soares - Molecular Psychiatry, 2022 - nature.com
The medial forebrain bundle—a white matter pathway projecting from the ventral tegmental
area—is a structure that has been under a lot of scrutinies recently due to its implications in …

[HTML][HTML] Neuromodulation of OCD: A review of invasive and non-invasive methods

A Kammen, J Cavaleri, J Lam, AC Frank… - Frontiers in …, 2022 - frontiersin.org
Early research into neural correlates of obsessive compulsive disorder (OCD) has focused
on individual components, several network-based models have emerged from more recent …

Potential optimization of focused ultrasound capsulotomy for obsessive compulsive disorder

J Germann, GJB Elias, C Neudorfer, A Boutet… - Brain, 2021 - academic.oup.com
Obsessive-compulsive disorder is a debilitating and often refractory psychiatric disorder.
Magnetic resonance-guided focused ultrasound is a novel, minimally invasive …