Pathogenicity and virulence of Hepatitis B virus

YC Chuang, KN Tsai, JHJ Ou - Virulence, 2022 - Taylor & Francis
Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

[HTML][HTML] Overview of hepatitis B virus mutations and their implications in the management of infection

P Caligiuri, R Cerruti, G Icardi… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) affects approximately two billion people worldwide and more than
240 million people in the world are currently chronic carrier that could develop serious …

[HTML][HTML] Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from randomized clinical trials

E Gane, YS Lim, JB Kim, V Jadhav, L Shen… - Journal of …, 2023 - Elsevier
Background & Aims Current therapy for chronic hepatitis B virus (cHBV) infection involves
lifelong treatment. New treatments that enable HBV functional cure would represent a …

[HTML][HTML] Hepatitis B virus and its sexually transmitted infection-an update

T Inoue, Y Tanaka - Microbial cell, 2016 - ncbi.nlm.nih.gov
Epidemiology: incidence and prevalence: About 5% of the world's population has chronic
hepatitis B virus (HBV) infection, and nearly 25% of carriers develop chronic hepatitis …

[HTML][HTML] The cGAS-STING pathway: novel perspectives in liver diseases

D Xu, Y Tian, Q Xia, B Ke - Frontiers in Immunology, 2021 - frontiersin.org
Liver diseases represent a major global health burden accounting for approximately 2
million deaths per year worldwide. The liver functions as a primary immune organ that is …

[HTML][HTML] Recent advances in hepatitis B treatment

GM Prifti, D Moianos, E Giannakopoulou, V Pardali… - Pharmaceuticals, 2021 - mdpi.com
Hepatitis B virus infection affects over 250 million chronic carriers, causing more than
800,000 deaths annually, although a safe and effective vaccine is available. Currently used …

[HTML][HTML] Small hepatitis B virus surface antigen promotes malignant progression of hepatocellular carcinoma via endoplasmic reticulum stress-induced FGF19/JAK2 …

S Wu, S Ye, X Lin, Y Chen, YI Zhang, Z Jing, W Liu… - Cancer Letters, 2021 - Elsevier
Chronic hepatitis B virus (HBV) infection is one of the major global health problems.
Although the small protein of hepatitis B virus surface antigen (HBsAg), SHBs, is the most …

Hepatitis B virus small envelope protein promotes hepatocellular carcinoma angiogenesis via endoplasmic reticulum stress signaling to upregulate the expression of …

SX Wu, SS Ye, YX Hong, Y Chen, B Wang… - Journal of …, 2022 - Am Soc Microbiol
Hepatocellular carcinoma (HCC) is a hypervascular tumor, and accumulating evidence has
indicated that stimulation of angiogenesis by hepatitis B virus (HBV) may contribute to HCC …

[HTML][HTML] A global view to HBV chronic infection: evolving strategies for diagnosis, treatment and prevention in immunocompetent individuals

LA Nicolini, A Orsi, P Tatarelli, C Viscoli… - International Journal of …, 2019 - mdpi.com
Hepatitis B Virus (HBV) is a significant public health challenge. Around 250 million people
live with chronic HBV infection. With a global approach to this issue, we focus on new …

Advances in isothermal nucleic acid amplification methods for hepatitis B virus detection

H Li, W Song, H Li, J Cui, Y Xie, B Wu, R Chen - Analyst, 2023 - pubs.rsc.org
Hepatitis B virus (HBV) infection is a major global health problem of widespread concern.
Clinically, serological assays are the most widely used diagnostic tests for HBV infection …