A murine cell line (BV-2) has been generated by infecting primary microglial cell cultures
with a-raf/v-myc oncogene carrying retrovirus (J2). BV-2 cells expressed nonspecific …

Picolinic acid, a catabolite of L-tryptophan, activates the transcription of the inducible nitric
oxide synthase gene (iNOS) in IFN-gamma-treated murine macrophages. We performed …

Recent studies have implicated long noncoding RNAs (lncRNAs) as regulators of many
important biological processes. Here we report on the identification and characterization of a …

Nitric oxide synthase (NOS) catalyzes the production of nitric oxide (NO), a short-lived
radical gas with physiological or pathophysiological roles in nearly every organ system. The …

To explore regulation of potentially lethal responses to bacterial lipopolysaccharide (LPS),
we used differential display under LPS-free conditions to compare macrophage cell lines …

Burkholderia cenocepacia is an opportunistic pathogen of the cystic fibrosis lung that elicits
a strong inflammatory response. B. cenocepacia employs a type VI secretion system (T6SS) …

Cell surface components of pathogens, such as lipopolysaccharide (LPS), are an important
signal for receptor‐mediated activation of immune cells. Here we demonstrate that DNA of …

IFN-γ induces a number of cellular programs functional in innate and adaptive resistance to
infectious pathogens. It has recently become clear that the complete cellular response to IFN …

Fe3O4 nanoparticles are the most widely used magnetic nanoparticles in the biomedicine
field. The biodistribution of most nanoparticles in vivo is determined by the capture of …

IFN-γ orchestrates a potent antimicrobial host response. However, the underlying molecular
basis for this immunological defense system is largely unknown. In a systematic approach to …