Advancements in liposome technology: Preparation techniques and applications in food, functional foods, and bioactive delivery: A review

KK Ajeeshkumar, PA Aneesh, N Raju… - … Reviews in Food …, 2021 - Wiley Online Library
Liposomes play a significant role in encapsulation of various bioactive compounds (BACs),
including functional food ingredients to improve the stability of core. This technology can be …

Improvement strategies for the oral bioavailability of poorly water-soluble flavonoids: An overview

J Zhao, J Yang, Y Xie - International journal of pharmaceutics, 2019 - Elsevier
Although flavonoid compounds have various pharmacological applications, they generally
exhibit low oral bioavailability due to their poor aqueous solubility. To address this problem …

Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease …

X Wang, G Sun, T Feng, J Zhang, X Huang, T Wang… - Cell research, 2019 - nature.com
Recently, increasing evidence has suggested the association between gut dysbiosis and
Alzheimer's disease (AD) progression, yet the role of gut microbiota in AD pathogenesis …

Actions of brain-derived neurotrophin factor in the neurogenesis and neuronal function, and its involvement in the pathophysiology of brain diseases

T Numakawa, H Odaka, N Adachi - International journal of molecular …, 2018 - mdpi.com
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a
variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the …

Cholinergic system and its therapeutic importance in inflammation and autoimmunity

N Halder, G Lal - Frontiers in immunology, 2021 - frontiersin.org
Neurological and immunological signals constitute an extensive regulatory network in our
body that maintains physiology and homeostasis. The cholinergic system plays a significant …

TrkB/BDNF signaling pathway and its small molecular agonists in CNS injury

Y Wang, J Liang, B Xu, J Yang, Z Wu, L Cheng - Life sciences, 2024 - Elsevier
As one of the most prevalent neurotrophic factors in the central nervous system (CNS), brain-
derived neurotrophic factor (BDNF) plays a significant role in CNS injury by binding to its …

Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer's disease mouse model

C Chen, EH Ahn, SS Kang, X Liu, A Alam, K Ye - Science advances, 2020 - science.org
The gut-brain axis is bidirectional, and gut microbiota influence brain disorders including
Alzheimer's disease (AD). CCAAT/enhancer binding protein β/asparagine endopeptidase …

Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer's disease

Y Xu, C Jiang, J Wu, P Liu, X Deng… - CNS Neuroscience …, 2022 - Wiley Online Library
Introduction Alzheimer's disease (AD) is the most common neurodegenerative disorder that
causes dementia and affects millions of people worldwide. Although it has devastating …

Brain-derived neurotrophic factor signaling in the pathophysiology of Alzheimer's disease: Beneficial effects of flavonoids for neuroprotection

T Numakawa, H Odaka - International Journal of Molecular Sciences, 2021 - mdpi.com
The function of the brain-derived neurotrophic factor (BDNF) via activation through its high-
affinity receptor Tropomyosin receptor kinase B (TrkB) has a pivotal role in cell …

Regulation of BDNF-TrkB signaling and potential therapeutic strategies for Parkinson's disease

W Jin - Journal of clinical medicine, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase
receptor type B (TrkB) are widely distributed in multiple regions of the human brain …