Microplastics–A Growing Concern as Carcinogens in Cancer Etiology: Emphasis on Biochemical and Molecular Mechanisms
N Kumar, M Lamba, AK Pachar, S Yadav… - Cell Biochemistry and …, 2024 - Springer
In today's world, the widespread presence of microplastics is undeniable, with
concentrations found in various environments, including up to 1000 particles per liter in …
concentrations found in various environments, including up to 1000 particles per liter in …
[HTML][HTML] Application of organoid technology in the human health risk assessment of microplastics: A review of progresses and challenges
J Cong, J Wu, Y Fang, J Wang, X Kong, L Wang… - Environment …, 2024 - Elsevier
Microplastic (MP) pollution has become a global environmental issue, and increasing
concern has been raised about its impact on human health. Current studies on the toxic …
concern has been raised about its impact on human health. Current studies on the toxic …
[HTML][HTML] Aerosol exposure at air-liquid-interface (AE-ALI) in vitro toxicity system characterisation: Particle deposition and the importance of air control responses
A Buckley, C Guo, A Laycock, X Cui… - Toxicology in Vitro, 2024 - Elsevier
Experimental systems allowing aerosol exposure (AE) of cell cultures at the air-liquid-
interface (ALI) are increasingly being used to assess the toxicity of inhaled contaminants as …
interface (ALI) are increasingly being used to assess the toxicity of inhaled contaminants as …
[HTML][HTML] Assessing toxicity of amorphous nanoplastics in airway-and lung epithelial cells using air-liquid interface models
IF Gosselink, FJ van Schooten, MJ Drittij, EM Höppener… - Chemosphere, 2024 - Elsevier
Background Inhalation is one of the main exposure routes to nanoplastics. Knowledge of the
toxicological impact of nanoplastics on the airway-and lung epithelium is limited and almost …
toxicological impact of nanoplastics on the airway-and lung epithelium is limited and almost …
Polystyrene nanoplastics mediate oxidative stress, senescence, and apoptosis in a human alveolar epithelial cell line
C Milillo, E Aruffo, P Di Carlo, A Patruno… - Frontiers in Public …, 2024 - frontiersin.org
Background Nanoplastics, an emerging form of pollution, are easily consumed by organisms
and pose a significant threat to biological functions due to their size, expansive surface area …
and pose a significant threat to biological functions due to their size, expansive surface area …
Mapping micro (nano) plastics in various organ systems: their emerging links to human diseases?
Y Luo, X Xu, Q Yin, S Liu, M Xing, X Jin, L Shu… - TrAC Trends in …, 2024 - Elsevier
Abstract Micro (nano) plastic (MNP) contamination has become an urgent global
environmental issue, causing immeasurable potential harm to humans. However, direct …
environmental issue, causing immeasurable potential harm to humans. However, direct …
Mutational landscape induced by chronic exposure to environmental PM10 and PM2. 5 in A549 lung epithelial cell
EM Quezada-Maldonado, D Cerrato-Izaguirre… - Chemosphere, 2024 - Elsevier
Exposure to particulate matter (PM) has been linked to an increased risk of multiple
diseases, primarily lung cancer, through various molecular mechanisms. However, the …
diseases, primarily lung cancer, through various molecular mechanisms. However, the …
[HTML][HTML] Characterization of airborne endotoxin in personal exposure to fine particulate matter (PM2. 5) and bioreactivity for elderly residents in Hong Kong
The heavy metals and bioreactivity properties of endotoxin in personal exposure to fine
particulate matter (PM 2.5) were characterized in the analysis. The average personal …
particulate matter (PM 2.5) were characterized in the analysis. The average personal …
OCTN1 mediates acetylcholine transport in the A549 lung cancer cells: possible pathophysiological implications
L Pochini, GE Tedesco, T Mazza, M Scalise… - Frontiers in Molecular …, 2024 - frontiersin.org
A role for acetylcholine in cell proliferation, epithelial mesenchymal transition and invasion
has been well assessed and related to the presence of the non-neuronal cholinergic system …
has been well assessed and related to the presence of the non-neuronal cholinergic system …
[HTML][HTML] Unveiling the potential of intranasal delivery of renin-angiotensin system drugs: Insights on the pharmacokinetics of irbesartan
F Gouveia, A Carona, M Lacerda, J Bicker… - Biochemical …, 2024 - Elsevier
The therapeutic interest of renin-angiotensin system (RAS) drugs for the treatment of
neuroinflammation has been recently acknowledged. Nevertheless, most RAS drugs display …
neuroinflammation has been recently acknowledged. Nevertheless, most RAS drugs display …