Frontotemporal lobar degeneration
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …
dementia and presents with early social–emotional–behavioural and/or language changes …
[HTML][HTML] An update on genetic frontotemporal dementia
CV Greaves, JD Rohrer - Journal of neurology, 2019 - Springer
Frontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders,
with around 30% of patients having a strong family history. The majority of that heritability is …
with around 30% of patients having a strong family history. The majority of that heritability is …
[HTML][HTML] Early-onset Alzheimer's disease: what is missing in research?
Abstract Purpose of Review Early-onset Alzheimer's disease (EOAD), defined as
Alzheimer's disease (AD) occurring before age 65, is significantly less well studied than the …
Alzheimer's disease (AD) occurring before age 65, is significantly less well studied than the …
[HTML][HTML] Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study
KM Moore, J Nicholas, M Grossman… - The Lancet …, 2020 - thelancet.com
Background Frontotemporal dementia is a heterogenous neurodegenerative disorder, with
about a third of cases being genetic. Most of this genetic component is accounted for by …
about a third of cases being genetic. Most of this genetic component is accounted for by …
Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues
R Ferrari, C Manzoni, J Hardy - Neurobiology of aging, 2019 - Elsevier
Frontotemporal lobar degeneration (FTLD) is the second most common form of dementia
after Alzheimer's disease. The study and the dissection of FTLD is complex due to its clinical …
after Alzheimer's disease. The study and the dissection of FTLD is complex due to its clinical …
Epigenetic clock acceleration is linked to age at onset of parkinson's disease
X Tang, P Gonzalez‐Latapi, C Marras… - Movement …, 2022 - Wiley Online Library
Background Aging is the strongest risk factor for Parkinson's disease (PD), which is a
clinically heterogeneous movement disorder with highly variable age at onset. DNA …
clinically heterogeneous movement disorder with highly variable age at onset. DNA …
C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies
SC Vatsavayai, AL Nana, JS Yokoyama… - Acta …, 2019 - Springer
What are the most important and treatable pathogenic mechanisms in C9orf72-FTD/ALS?
Model-based efforts to address this question are forging ahead at a blistering pace, often …
Model-based efforts to address this question are forging ahead at a blistering pace, often …
Recent advances in the genetics of frontotemporal dementia
Abstract Purpose of Review In this review, we highlight recent advances in the human
genetics of frontotemporal dementia (FTD). In addition to providing a broad survey of genes …
genetics of frontotemporal dementia (FTD). In addition to providing a broad survey of genes …
Implications of microglia in amyotrophic lateral sclerosis and frontotemporal dementia
H Haukedal, K Freude - Journal of molecular biology, 2019 - Elsevier
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are
neurodegenerative disorders with clear similarities regarding their clinical, genetic and …
neurodegenerative disorders with clear similarities regarding their clinical, genetic and …
[HTML][HTML] Genetic architecture of common non-Alzheimer's disease dementias
Frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and vascular dementia
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …