Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

The use of systemic anticancer chemotherapy is intrinsically limited by its toxicity. Whether
dealing with small molecules or biopharmaceuticals, after systemic administration, small …

Modern drug delivery technology began in 1952 with the advent of the Spansule® sustained-
release capsule technology, which can deliver a drug for 12 h after oral administration …

Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

Tumor-positive resection margins after surgery can result in tumor recurrence and
metastasis. Although adjuvant postoperative radiotherapy and chemotherapy have been …

Transdermal drug delivery is of vital importance for medical treatments. However, user
adherence to long-term repetitive drug delivery poses a grand challenge. Furthermore, the …

With over 2 million cancer cases and over 600,000 cancer-associated deaths predicted in
the US for 2022, this life-debilitating disease continuously impacts the lives of people across …