Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal neurodegenerative disease
characterized by degeneration of upper and lower motor neurons in the brain and spinal …

We introduce APEX-seq, a method for RNA sequencing based on direct proximity labeling of
RNA using the peroxidase enzyme APEX2. APEX-seq in nine distinct subcellular locales …

Stochastic resetting is prevalent in natural and man-made systems, giving rise to a long
series of nonequilibrium phenomena. Diffusion with stochastic resetting serves as a …

Nuclear export of mRNAs is a crucial step in the regulation of gene expression, linking
transcription in the nucleus to translation in the cytoplasm. Although important components …

The in vivo characterization of the exact copy number and the specific function of each
composite protein within the nuclear pore complex (NPC) remains both desirable and …

Nuclear pore complexes (NPCs) embedded within the nuclear envelope mediate rapid,
selective and bidirectional traffic between the cytoplasm and the nucleoplasm. Deciphering …

Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step
of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of …

Nuclear export of messenger RNA (mRNA) through the nuclear pore complex (NPC) is an
indispensable step to ensure protein translation in the cytoplasm of eukaryotic cells. mRNA …

Many aspects of the behaviors of physical, chemical, and biological systems can be
understood simply in terms of the dynamics of the averaged state variables and their …