BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

Chemotherapy treatment is a mainstay of anticancer regimens, significantly contributing to
the recent increase in childhood cancer survival rates. Conventional cancer therapy targets …

The treatment of childhood cancer with chemotherapy drugs can result in infertility in
adulthood. Newer generations of drugs are developed to replace parent drugs, with the …

Decellularized scaffolds have been found to be excellent platforms for tissue engineering
applications. The attempts are still being made to optimize a decellularization protocol with …

Chemotherapy can affect testis development of young boys with cancer, reducing the
chances of fatherhood in adulthood. Studies using experimental models are needed to …

Electrospun nanofiber matrices sufficiently mimic the structural morphology of natural
extracellular matrix. In this study, we aimed to examine the effects of agar/polyvinyl alcohol …

We have recently reported that antioxidant supplements enhance the efficacy of
cryopreserved spermatogonial stem cells. Melatonin is considered a free radical scavenger …

The unclear bio‐safety issue and potential risk of nanoparticles (NPs) on various organelles
can be considered as a major challenge. In the present study, we have assessed the green …

Background Cancer is the second leading cause of human death. Therefore,
comprehensive research and the appropriate tools are needed in this field. Animal models …

Background Some male survivors of childhood cancer are suffering from azoospermia. In
addition, spermatogonial stem cells (SSCs) are necessary for the improvement of …