Current research efforts on neurological diseases are focused on identifying novel disease
biomarkers to aid in diagnosis, provide accurate prognostic information and monitor disease …

▪ Abstract Tumors of the central nervous system (CNS) can be devastating because they
often affect children, are difficult to treat, and frequently cause mental impairment or death …

Conclusion In conclusion, direct genetic alterations leading to deregulated PI3K/Akt
signalling are common in a significant fraction of human malignancies. The forthcoming …

Ependymal tumors are heterogeneous with regard to morphology, localization, age at first
clinical manifestation, and prognosis. Several molecular alterations have been reported in …

Glioblastomas develop de novo (primary glioblastomas) or through progression from low-
grade or anaplastic astrocytoma (secondary glioblastomas). There is increasing evidence …

Background Oral squamous cell carcinoma (SCC) is associated with oral microbial
dysbiosis. In this unique study, we compared pre-to post-treatment salivary microbiome in …

De novo glioblastomas develop in older patients without prior clinical history of less
malignant tumors. Progressive glioblastomas are common among younger patients and …

The gene deleted in malignant brain tumors 1 (DMBT1) has been proposed as a candidate
tumor suppressor for brain, gastrointestinal, and lung cancer. It codes for a protein of …

Allelic loss of 10q is a common genetic event in malignant gliomas, with three 10q tumor
suppressor genes, ERCC6, PTEN, and DMBT1, putatively implicated in the most common …

Astrocytic brain tumors are the most frequent human gliomas and they include a wide range
of neoplasms with distinct clinical, histopathologic, and genetic features. Diffuse …